Diagnostic ability of macular ganglion cell asymmetry in Preperimetric Glaucoma

BMC Ophthalmology

Table 5 P values for pairwise comparison of AUROC values, pAUROC values, and sensitivities at fixed specificities between the best measure of each GCIPL asymmetry analysis and cpRNFL, GCIPL, and ONH parameters

	AUROC	pAUROC at 90% specificity	pAUROC at 95% specificity	Sensitivity at 90% specificity	Sensitivity at 95% specificity
IT–SN vs. IT GCIPL thickness	0.277	0.151	0.340	0.474	0.767
IT–SN vs. average cpRNFL thickness	0.398	0.870	0.060	0.304	0.029
IT–SN vs. average C/D	0.618	0.441	0.484	0.667	0.225
IT/IN vs. IT GCIPL thickness	0.141	0.636	0.883	0.250	1.00
IT/IN vs. average cpRNFL thickness	0.247	0.268	0.141	0.553	0.059
IT/IN vs. average C/D	0.414	0.950	0.775	0.386	0.359
Log (IT/SN) vs. IT GCIPL thickness	0.395	0.226	0.290	0.322	0.083
Log (IT/SN) vs. average cpRNFL thickness	0.705	0.017	0.011	0.007	< 0.001
Log (IT/SN) vs. average C/D	0.845	0.145	0.025	0.203	0.008

AUROC, area under the receiver operating characteristic curves; pAUROC, partial area under the receiver operating characteristic curves; GCIPL, ganglion cell-inner plexiform layer; cpRNFL, circumferential peripapillary retinal nerve fiber layer; C/D, cup-to-disc ratio; IT, inferotemporal; SN, superonasal; IN, inferonasal

ISSN: 1471-2415