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Table 2 Main baseline demographic and clinical characteristics according to the diabetic macular edema (DME) subtypes

From: Intravitreal dexamethasone implant Ozurdex® in naïve and refractory patients with different subtypes of diabetic macular edema

Characteristic

DRT (n = 20)

CME (n = 41)

SRD (n = 23)

Pa

Age, years

 Mean (SD)

72.5 (7.2)

72.4 (8.7)

67.6 (10.9)

0.0987

 95% CI

69,1 to 75,8

69.6 to 75.2

62.9 to 72.3

 

HbA1c, (%)

 Mean (SD)

7.4 (0.9)

7.6 (1.0)

7.7 (0.8)

0.7371

 95% CI

7.0 to 7.9

7.3 to 7.9

7.3 to 8.0

 

Sex, n (%)

 Man

14 (70.0)

25 (61.0)

19 (82.6)

0.1981b

 Woman

6 (30.0)

16 (39.0)

4 (17.4)

 

Eye, n (%)

 Right

12 (60.0)

19 (46.3)

14 (60.9)

0.4303b

 Left

8 (40.0)

22 (53.7)

9 (39.1)

 

Type of patient, n (%)

 Naïve

6 (30.0)

13 (31.7)

10 (43.5)

0.5653b

 Non-naïve

14 (70.0)

28 (68.3)

13 (56.5)

 

Visual Acuity**

 Mean (SD)

64.8 (10.1)

58.8 (16.2)

60.9 (14.6)

0.3272

 95% CI

60.0 to 69.5

53.7 to 63.9

54.5 to 67.2

 

Number of anti-VEGF injections

 Mean (SD)

5.3 (4.9)

5.1 (4.9)

3.1 (3.2)

0.1877

 95% CI

3.0 to 7.6

3.5 to 6.6

1.7 to 4.5

 

CMT, μm

 Mean (SD)

352.6 (38.4)

459.4 (141.8)*

533.8 (149.2)*

< 0.0001

 95% CI

334,6 to 370,6

414,7 to 504,2

469,3 to 598,3

 
  1. DRT diffuse retinal thickness, CME cystoid macular edema, SRD serous retinal detachment, SD standard deviation, CI confidence interval, VEGF vascular endothelial grow factor, CMT central macular thickness
  2. aOne-way ANOVA test
  3. bChi-square test
  4. *Significantly different from DRT, p < 0.001
  5. **Letters in the Early Treatment Diabetic Retinopathy Study (ETDRS) charts