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Fig. 8 | BMC Ophthalmology

Fig. 8

From: Safety and efficacy of wiping lid margins with lid hygiene shampoo using the “eye brush”, a novel lid hygiene item, in healthy subjects: a pilot study

Fig. 8

a-c Efficacy study results based on the lid staining scores. Fluorescein-stained 0.3% Tarivid ointment was used for grading (Table 2) after wiping the lid margins using tap water alone, Eye Shampoo, the Eye Brush, or both Eye Shampoo and the Eye Brush in subjects with normal meibomian glands. The wiping efficacies of each of the four lid hygiene methods were compared (a). The efficacy using both Eye Shampoo and the Eye Brush was compared with that using Eye Shampoo only (b) or the Eye Brush only (c) in one-tailed hypothesis (water < Eye Shampoo < Eye Shampoo and Eye Brush, water < Eye Brush < Eye Shampoo and Eye Brush) tests. In the box-and-whisker plots, the bottom of the box indicates the first quartile, and the top of the box indicates the third quartile. The band inside the box represents the median. To highlight suspected outliers, the upper whisker is set as the maximum or the third quartile+ 1.5 × IQR. The lower whisker indicates the minimum or the first quartile-1.5 × IQR. The bee swarm plot is a one-dimensional scatter plot with non-overlapping points. Note that because the placement of the dots in figures is randomly determined in the bee swarm plot, the dots are sometimes merged. * Significant improvement; P < 0.0083 [0.05/6 = 0.0083, Bonferroni correction] (a) and * Significant improvement; P < 0.025 [0.05/2 = 0.025, Bonferroni correction] (b, c) are demonstrated

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