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Fig. 2 | BMC Ophthalmology

Fig. 2

From: Ocular toxicity of intravitreal melphalan for retinoblastoma in Chinese patients

Fig. 2

Panretinopathy and with optic atrophy. 5 cases with optic atrophy before and after IVM have been shown in Fig. 5.The recurrence of a retinoblastoma with diffuse vitreous seeds. (a) Eight months after three rounds of IAC and four injections showing panretinopathy with optic atrophy (b).Persistent seeds after three rounds of IAC.(c) Twelve months after three injections showing panretinopathy and vascular occlusion with optic atrophy.(d) Persistent seeds after five cycles of chemotherapy. (e)Four months after three doses of IVM injections showing complete control of vitreous seeds and vascular occlusion with optic atrophy.(f) Refractory diffuse vitreous seeds after six cycles of chemotherapy. (g) Three months after two doses of IVM injections showing complete control of vitreous seeds and hemorrhagic retinopathy with optic atrophy(h). Persistent seeds after three rounds of IAC(i) Eighteen months after two injections showing vascular occlusion with optic atrophy.(j)

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