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Fig. 5 | BMC Ophthalmology

Fig. 5

From: Ocular toxicity of intravitreal melphalan for retinoblastoma in Chinese patients

Fig. 5

Vascular occlusion. 6 cases with vascular occlusion before and after IVM have been shown in Fig. 4. Persistent seeds after three rounds of IAC(a)Three months after three injections showing branch vascular occlusion(b). Refractory focal vitreous seeds after six cycles of chemotherapy(c). Six months after one injection showing branch vascular occlusion and retinopathy. (d) Persistent focal seeds after six cycles of intravenous chemotherapy and two IVM injections.(e) One month after another IVM injection showing hemorrhagic retinopathy and vascular occlusion.(f) Persistent seeds after six cycles of intravenous chemotherapy(g). Ten months after three injection showing branch vascular occlusion.(h) Refractory diffuse vitreous seeds after three rounds of IAC.(i) Eight months after five injection showing branch vascular occlusion and pupillary synechiae.(j)Persistent seeds after four rounds of IAC.(k) Eight months after four injection showing branch vascular occlusion and pupillary synechiae. (l) The vascular occlusions were marked by arrows

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