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Table 1 Characteristics of infants with Type 1 ROP after the post-menstrual age of 40 weeks

From: Ranibizumab injection and laser photocoagulation to treat type 1 retinopathy of prematurity after 40 weeks post menstrual age: a retrospective case series study

Variables All infants Comparison between Group 1 and 2
  Group 1 Group 2 p value
  (Primary IVR) (Primary laser)  
Patients, n 14 9 5 /
Male, n (%) 8 7 (78%) 0 (0%) 0.021* (Fisher’s exact test)
GA, weeks (mean ± SD) 28.9 ± 2.3 29.0 ± 2.2 28.8 ± 2.6 0.882 (Student t-test)
(range) (26.0–33.0) (27.0–33.0) (26.0–32.0)  
BW, grams (mean ± SD) 1227.1 ± 347.9 1200.5 ± 360.3 1275.0 ± 359.6 0.717 (Student t-test)
(range) (815–2000) (815–2000) (980–1800)  
PMA at diagnosis, weeks [mean ± SD (range)] 41.4 ± 2.2 40.8 ± 1.0 (40–43) 42.6 ± 3.4 (40–48) 0.518 (Mann-Whitney test)
Follow-up, months [mean ± SD (range)] 12.5 ± 6.9 (6–24) 11.0 ± 5.9 (6–24) 15.2 ± 8.3 (6–24) 0.290 (Student t-test)
Eyes, n 27 17 10  
Zone 2 stage 3 with plus, n (%) 20 14 (82%) 6 (60%) 0.365 (Pearson’s Chi-squared test)
Zone 2 stage 2 with plus, n (%) 7 3 (18%) 4 (40%) /
Posterior zone 2 disease   12 (86%) 0 (0) < 0.001(Fisher’s exact test)
Fibrotic ridges, n (%) 17 12 (70%) 5 (50%) 0.415
Hemorrhage on fibrovascular ridge, n, (%) 11 10 (59%) 1 (10%) 0.018* (Fisher’s exact test)
  1. BW birth weight, DD disc diameter, GA gestational age, IVR intravitreal injection of ranibizumab, PMA postmenstrual age, ROP retinopathy of prematurity, SD standard deviation
  2. *significant between-group difference