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Fig. 4 | BMC Ophthalmology

Fig. 4

From: Effects of concentration of amyloid β (Aβ) on viability of cultured retinal pigment epithelial cells

Fig. 4

Induction of VEGF-A and PEDF expression in ARPE cells by exposure to Aβ 1–40. ARPE-19 cells were exposed to 25 μM Aβ 1–40 for 24 h, and the expressions of the mRNAs of VEGF-A and PEDF were determined by real-time RT-PCR using β-actin as an endogenous control. The level of the mRNA of VEGF-A is significantly increased only in the 25 μM Aβ group (A). On the other hand, the level of the mRNA of PEDF is increased by 5 μM Aβ 1–40 and is also increased by 25 μM Aβ 1–40 exposure (B). Data are the means ± SEMs for each group (n = 4)

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