Table 2 Univariate and Multivariate Logistic Regression Analysis of Risk Factors of diagnostic timing in FEVR patients
Risk factors | FEVR diagnosed pre-operatively (n = 23) | FEVR diagnosed intra−/post-operatively (n = 25) | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | |||
Preoperative ocular manifestations, n (%) (no. of patients) | ||||||
RD only | 19 (82.6) | 8 (32.0) | 0.099 (0.025–0.389) | 0.001 | 0.104 (0.015–0.725) | 0.022 |
Other manifestations except/without RD | 4 (17.4) | 17 (68.0) | ||||
Father/mother FA, n (%) | ||||||
- | 2 (8.7) | 9 (36.0) | 0.141 (0.023–0.857) | 0.033 | 0.105 (0.013–0.855) | 0.035 |
+ | 11 (47.8) | 7 (28.0) | ||||
N/A | 10 (43.5) | 9 (36.0) | ||||
Year of diagnosis, n (%) | ||||||
2010–2015 | 7 (30.4) | 17 (68.0) | 0.161 (0.044–0.583) | 0.005 | ||
2016–2018 | 16 (69.6) | 8 (32.0) | ||||
Year at initial clinic visit (years), n (%) | ||||||
2007–2014 | 7 (30.4) | 19 (76.0) | 0.138 (0.039–0.496) | 0.002 | ||
2015–2018 | 16 (69.6) | 6 (24.0) | ||||
Wide-angle fundus imaging preoperatively, n (%) | ||||||
No | 6 (26.1) | 20 (80.0) | 0.088 (0.023–0.341) | 0.000 | ||
Yes | 17 (73.9) | 5 (20.0) | ||||
Ocular trauma, n (%) | ||||||
No | 17 (73.9) | 24 (96.0) | 0.118 (0.013–1.072) | 0.058 | ||
Yes | 6 (26.1) | 1 (4.0) | ||||
Clinical stage in contralateral eye, n (%) | ||||||
Stage 1-Stage 2 | 17 (73.9) | 23 (92.0) | 4.059 (0.728–22.637) | 0.110 | ||
Stage 3-Stage 5 | 6 (26.1) | 2 (8.0) | ||||
Age at initial clinic visit (years), n (%) | ||||||
0.25–12 | 10 (43.5) | 16 (64.0) | 0.433 (0.136–1.381) | 0.157 | ||
13–58 | 13 (56.5) | 9 (36.0) | ||||
Gender, n (%) | ||||||
Female | 4 (17.4) | 9 (36.0) | 0.374 (0.097–1.447) | 0.154 | ||
Male | 19 (82.6) | 16 (64.0) | ||||
Preterm birth, n (%) | ||||||
Yes | 0 (0.0) | 1 (4.0) | 0.000 (0.000-) | 1.000 | ||
No | 23 (100.0) | 24 (96.0) | ||||
Surgery in other hospital before first clinic visit, n (%) | ||||||
No | 21 (91.3) | 19 (76.0) | 3.316 (0.596–18.451) | 0.171 | ||
Yes | 2 (8.7) | 6 (24.0) | ||||
Ocular involvement, n (%) | ||||||
Bilateral | 6 (26.1) | 5 (20.0) | 0.908 (0.253–3.251) | 0.882 | ||
Unilateral | 17 (73.9) | 20 (80.0) | ||||
Clinical stage of patients at initial presentation, n (%)a | ||||||
Stage 1-Stage 4 | 14 (60.9) | 11 (44.0) | 1.980 (0.626–6.259) | 0.245 | ||
Stage 5 | 9 (39.1) | 14 (56.0) | ||||
Initial surgery in our hospital, n (%) | ||||||
SB/SE | 7 (30.4) | 5 (20.0) | 1.750 (0.466–6.568) | 0.407 | ||
PPV/L | 16 (69.6) | 20 (80.0) | ||||