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Table 2 Results of all cases

From: Retinal function determined by flicker ERGs before and soon after intravitreal injection of anti-VEGF agents

n = 79 (male: 44, female: 35)

mean age

68.9 ± 12.6 y.o.

 

injected eye

Phase 1

Phase 2

Phase 3

repeated measure test

implicit time

31.2 ± 3.2

31.7 ± 3.1a

32.2 ± 3.3a

p < 0.00001

(msec.)

 

p = 0.00034

p < 0.00001

amplitude

8.7 ± 5.7

7.9 ± 6.1

9.5 ± 8.9

p = 0.12

(uV)

 

p = 0.5

p = 0.92

non-injected eye

Phase 1

Phase 2

Phase 3

repeated measure test

implicit time

30.5 ± 3.3

31.1 ± 3.18a

31.3 ± 3.4a

p = 0.000018

(msec.)

 

p = 0.0084

p = 0.00002

amplitude

9.4 ± 6.5

9.2 ± 6.7

9.5 ± 6.2

p = 0.72

(uV)

 

p = 1

p = 1

  1. The results of 28 Hz flicker ERG components including all patients before classification by disease of by injected agent. The ERGs were recorded before the injection (Phase 1), within 2 h after the injection (Phase 2), and 2 to 24 h after the injection (Phase 3)
  2. mean ± standard deviation
  3. a; significant difference by the repeated measure test and by the post hoc test compared to Phase 1