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Table 4 Changes of Schirmer values between CN and DQ group

From: RETRACTED ARTICLE: Comparison of 0.05% cyclosporine and 3% diquafosol solution for dry eye patients: a randomized, blinded, multicenter clinical trial

 

0

4 weeks

12 weeks

Difference (0–4 weeks)a

Difference (0–12 weeks)a

P value (0–12 weeks)b

CN

8.67 ± 6.30 (2.00~35.00)

9.50 ± 6.21 (0.00~30.00)

10.14 ± 6.13 (0.00~30.00)

0.83 ± 5.26 (−17.00~14.00)

1.47 ± 6.20 (−20.00~19.00)

0.0031

DQ

7.96 ± 5.55 (1.00~30.00)

9.52 ± 6.71 (0.00~30.00)

9.02 ± 5.59 (0.00~35.00)

1.56 ± 5.45 (−14.00~20.00)

1.06 ± 6.32 (−16.00~15.00)

0.0643

P value

0.3955

0.9754

0.3675

0.9214

0.8597

 
  1. CN 0.05% cyclosporin nanoemusion (0.5 mg/mL), DQ 3% diquafosol sodium (30 mg/mL)
  2. aComparison between CN and DQ groups by Wilcoxon rank sum test
  3. bComparison among three groups by Kruskal-Wallis test