Fig. 2From: Scleritis and anterior uveitis may herald the development of an epibulbar tumor in patients with extranodal Rosai-Dorfman disease: a case reportPathological study of Rosai-Dorfman disease (RDD). a The excisional epibulbar nodule (Gross view). b Photomicrographs revealing RDD histiocytes with emperipolesis (arrows) (hematoxylin and eosin stain; original magnification, × 400). c, d Immunohistochemical photomicrograph displaying the histiocytes with positive nuclear and cytoplasmic staining for S-100 (c) but negative staining for CD1a (d). The arrow in Panel c marks emperipolesis (original magnification, × 400)Back to article page