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Fig. 2 | BMC Ophthalmology

Fig. 2

From: Scleritis and anterior uveitis may herald the development of an epibulbar tumor in patients with extranodal Rosai-Dorfman disease: a case report

Fig. 2

Pathological study of Rosai-Dorfman disease (RDD). a The excisional epibulbar nodule (Gross view). b Photomicrographs revealing RDD histiocytes with emperipolesis (arrows) (hematoxylin and eosin stain; original magnification, × 400). c, d Immunohistochemical photomicrograph displaying the histiocytes with positive nuclear and cytoplasmic staining for S-100 (c) but negative staining for CD1a (d). The arrow in Panel c marks emperipolesis (original magnification, × 400)

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