Covariate | Number of studies | Number of eyes | Sensitivity (95% CI) | P-value | Specificity (95% CI) | P-value |
---|---|---|---|---|---|---|
Ethnicity | ||||||
 Asian | 2 | 107 | 0.91 (0.80–1.00) | 0.69 | 0.82 (0.53–1.00) | 0.09 |
 Other races | 14 | 754 | 0.87 (0.80–0.93) |  | 0.97 (0.95–1.00) |  |
Type of study | ||||||
 Prospective | 5 | 301 | 0.93 (0.88–0.98) | 0.61 | 0.99 (0.96–1.00) | 0.08 |
 Retrospective | 8 | 473 | 0.79 (0.72–0.86) |  | 0.93 (0.87–1.00) |  |
Etiology | ||||||
 AMD | 7 | 560 | 0.89 (0.82–0.95) | 0.12 | 0.98 (0.94–1.00) | 0.44 |
 Other ocular diseases | 9 | 301 | 0.85 (0.76–0.94) |  | 0.97 (0.92–1.00) |  |
Reference standard | ||||||
 FA | 9 | 549 | 0.83 (0.76–0.90) | < 0.01 | 0.94 (0.88–1.00) | 0.09 |
 Other reference standards | 7 | 372 | 0.92 (0.86–0.97) |  | 0.99 (0.97–1.00) |  |
Type of device | ||||||
 AngioVue | 10 | 426 | 0.90 (0.86–0.95) | 0.09 | 0.96 (0.91–1.00) | 0.66 |
 other devices | 6 | 435 | 0.80 (0.72–0.87) |  | 0.98 (0.96–1.00) |  |
Sample size | ||||||
 ≥ 50 | 8 | 690 | 0.88 (0.81–0.95) | 0.12 | 0.96 (0.91–1.00) | 0.57 |
 < 50 | 8 | 171 | 0.86 (0.77–0.96) |  | 0.99 (0.96–1.00) |  |