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Table 2 Meta-regression and subgroup analyses for sensitivity and specificity

From: Diagnostic accuracy of optical coherence tomography angiography for choroidal neovascularization: a systematic review and meta-analysis

CovariateNumber of studiesNumber of eyesSensitivity (95% CI)P-valueSpecificity (95% CI)P-value
Ethnicity
 Asian21070.91 (0.80–1.00)0.690.82 (0.53–1.00)0.09
 Other races147540.87 (0.80–0.93) 0.97 (0.95–1.00) 
Type of study
 Prospective53010.93 (0.88–0.98)0.610.99 (0.96–1.00)0.08
 Retrospective84730.79 (0.72–0.86) 0.93 (0.87–1.00) 
Etiology
 AMD75600.89 (0.82–0.95)0.120.98 (0.94–1.00)0.44
 Other ocular diseases93010.85 (0.76–0.94) 0.97 (0.92–1.00) 
Reference standard
 FA95490.83 (0.76–0.90)< 0.010.94 (0.88–1.00)0.09
 Other reference standards73720.92 (0.86–0.97) 0.99 (0.97–1.00) 
Type of device
 AngioVue104260.90 (0.86–0.95)0.090.96 (0.91–1.00)0.66
 other devices64350.80 (0.72–0.87) 0.98 (0.96–1.00) 
Sample size
 ≥ 5086900.88 (0.81–0.95)0.120.96 (0.91–1.00)0.57
 < 5081710.86 (0.77–0.96) 0.99 (0.96–1.00)