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Table 2 Meta-regression and subgroup analyses for sensitivity and specificity

From: Diagnostic accuracy of optical coherence tomography angiography for choroidal neovascularization: a systematic review and meta-analysis

Covariate

Number of studies

Number of eyes

Sensitivity (95% CI)

P-value

Specificity (95% CI)

P-value

Ethnicity

 Asian

2

107

0.91 (0.80–1.00)

0.69

0.82 (0.53–1.00)

0.09

 Other races

14

754

0.87 (0.80–0.93)

 

0.97 (0.95–1.00)

 

Type of study

 Prospective

5

301

0.93 (0.88–0.98)

0.61

0.99 (0.96–1.00)

0.08

 Retrospective

8

473

0.79 (0.72–0.86)

 

0.93 (0.87–1.00)

 

Etiology

 AMD

7

560

0.89 (0.82–0.95)

0.12

0.98 (0.94–1.00)

0.44

 Other ocular diseases

9

301

0.85 (0.76–0.94)

 

0.97 (0.92–1.00)

 

Reference standard

 FA

9

549

0.83 (0.76–0.90)

< 0.01

0.94 (0.88–1.00)

0.09

 Other reference standards

7

372

0.92 (0.86–0.97)

 

0.99 (0.97–1.00)

 

Type of device

 AngioVue

10

426

0.90 (0.86–0.95)

0.09

0.96 (0.91–1.00)

0.66

 other devices

6

435

0.80 (0.72–0.87)

 

0.98 (0.96–1.00)

 

Sample size

 ≥ 50

8

690

0.88 (0.81–0.95)

0.12

0.96 (0.91–1.00)

0.57

 < 50

8

171

0.86 (0.77–0.96)

 

0.99 (0.96–1.00)

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