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Table 2 Results of Meta-analysis for Defocus Curve

From: Efficacy and safety of extended depth of focus intraocular lenses in cataract surgery: a systematic review and meta-analysis

Defocus levels

MD [95% CI]

P value

Heterogeneity

I2 (%)

P heterogeneity

EDOF vs. Monofocal IOLs

-0.01

−0.00 (− 0.10, 0.08)

0.81

89

0.0001

−0.50

−0.04 (− 0.09, 0.00)

0.07

25

0.26

−1.00

−0.16 (− 0.21, − 0.12)

< 0.00001

0

0.65

− 1.50

− 0.22 (− 0.31, − 0.13)

< 0.00001

63

0.07

−2.00

− 0.24 (− 0.29, − 0.19)

< 0.00001

8

0.34

− 2.50

− 0.22 (− 0.27, − 0.16)

< 0.00001

0

0.45

− 3.00

− 0.25 (− 0.31, − 0.18)

< 0.00001

37

0.20

−3.50

− 0.21 (− 0.26, − 0.16)

< 0.00001

0

0.94

−4.00

−0.21 (− 0.26, − 0.16)

< 0.00001

0

0.73

EDOF vs. Trifocal IOLs

0.00

−0.02 (− 0.07, 0.03)

0.40

59

0.06

−0.50

−0.03 (− 0.08, 0.01)

0.17

52

0.10

−1.00

−0.04 (− 0.10, 0.01)

0.11

55

0.08

−1.50

−0.01 (− 0.08, 0.07)

0.88

76

0.006

−2.00

0.03 (−0.01, 0.07)

0.19

0

0.96

−2.50

0.10 (0.06, 0.15)

< 0.00001

0

0.79

−3.00

0.17 (0.09, 0.26)

< 0.0001

65

0.04

−3.50

0.19 (0.07, 0.30)

0.002

68

0.04

−4.00

0.21 (0.07, 0.35)

0.003

79

0.008

  1. IOL intraocular lens, MD mean difference, CI confidence interval, I2 extent of inconsistency