Table 1 Completeness of data recorded in reported data sources
Country | Data source name (type) | Baseline status | Outcomes | |||||
|---|---|---|---|---|---|---|---|---|
Clinical | Treatment | Anti-VEGF | Safety | Human | Economic | |||
Australia | Fight Retinal Blindness (active disease registry) | +++ | ++ | +++ | +++ | +++ | – | – |
Australian Heart Eye Study (prospective cohort study) | ++ | – | + | + | – | – | – | |
Blue Mountains Eye Study (prospective cohort study) | +++ | + | + | – | – | – | ||
Macular Disease Foundation (active disease registry) | – | – | + | +++ | – | ++ | – | |
Melbourne Collaborative Cohort Study (prospective cohort study) | +++ | – | + | + | – | – | – | |
Canada | Southwestern Ontario Database (passive disease registry) | +++ | +++ | +++ | +++ | +++ | +++ | +++ |
British Columbia Ministry of Health Databases (administrative/claims database) | ++ | – | ++ | +++ | – | – | – | |
Quebec prescription and medical claims databases (administrative/claims database) | ++ | – | + | – | +++ | – | ++ | |
China | Beijing Eye Study (population-based longitudinal study) | +++ | +++ | +++ | – | – | – | – |
Denmark | Four referral centres in Denmark (unnamed – electronic medical records) | ++ | – | + | – | – | +++ | – |
France | Creteil Intercommunal University Hospital Eye Clinic (prospective cohort study) | ++ | +++ | ++ | +++ | – | ++ | +++ |
Retina France (cross-sectional study) | +++ | – | ++ | +++ | – | +++ | +++ | |
ALIENOR (prospective cohort study) | +++ | + | +++ | + | – | +++ | – | |
Germany | OCEAN (prospective cohort study) | ++ | +++ | +++ | +++ | – | +++ | ++ |
CAPTAIN (retrospective cohort study) | +++ | – | +++ | +++ | – | ++ | +++ | |
Bonn Ophthalmology online network (active disease registry) | + | ++ | ++ | +++ | – | – | +++ | |
Gutenberg Health Study (prospective cohort study) | +++ | +++ | + | + | – | – | – | |
FAM study (prospective cohort study) | +++ | – | ++ | + | – | – | – | |
Landschaftsverband Rheinland database (active disease registry) | ++ | – | – | + | – | – | – | |
Iceland | Age, Gene/Environment Susceptibility–Reykjavik Study (prospective cohort study) | +++ | – | – | + | – | – | – |
Japan | Japan Medical Data Centre (administrative/claims database) | ++ | – | ++ | +++ | – | – | +++ |
Hatoyama Cohort Study (prospective cohort study) | +++ | – | + | – | – | ++ | ++ | |
Hisayama study (prospective cohort study) | ++ | – | + | + | – | – | – | |
Multinational | AURA study | +++ | +++ | +++ | +++ | +++ | – | +++ |
The EPICOHORT study | ++ | +++ | +++ | +++ | +++ | – | – | |
European Genetics Database | +++ | +++ | +++ | +++ | – | – | ++ | |
IRISS | + | ++ | + | – | +++ | – | – | |
LUMINOUS study | ++ | +++ | +++ | +++ | +++ | – | +++ | |
VigiBase | +++ | ++ | ++ | +++ | +++ | – | – | |
Norway | Tromso Eye Study (population-based longitudinal study) | +++ | – | + | + | – | – | – |
Sweden | Swedish Macula Register (active disease registry) | +++ | +++ | +++ | +++ | +++ | +++ | +++ |
Swedish Lucentis Quality Registry (active disease registry) | ++ | +++ | +++ | +++ | +++ | +++ | ++ | |
UK | British Ophthalmological Surveillance Unit (electronic medical records) | ++ | ++ | +++ | +++ | +++ | – | +++ |
Medisoft (electronic medical records) | +++ | +++ | +++ | +++ | +++ | +++ | +++ | |
Scotland intravitreal ranibizumab treatment register (unnamed – electronic medical records) | +++ | +++ | +++ | +++ | +++ | – | +++ | |
UK Age-Related Macular Degeneration Electronic Medical Record Users Group (retrospective cohort study) | ++ | +++ | +++ | +++ | +++ | – | +++ | |
Unnamed tertiary referral clinic (active disease registry) | +++ | +++ | +++ | +++ | – | – | +++ | |
Gloucestershire NHS ophthalmology department (electronic medical records) | ++ | +++ | +++ | +++ | – | – | – | |
Medical Retina Clinic at King’s College London (electronic medical records) | +++ | +++ | +++ | +++ | – | – | ++ | |
Medical Retina Service, St Thomas’ Hospital (electronic medical records) | ++ | +++ | ++ | +++ | – | – | +++ | |
Belfast Health and Social Care Trust database (unnamed - electronic medical records) | ++ | – | ++ | +++ | +++ | – | – | |
The National Ophthalmology Database (active disease registry) | ++ | – | – | + | – | – | – | |
Grampian University Hospitals (electronic medical records) | ++ | – | – | + | – | – | – | |
English National Hospital Episode Statistics (electronic medical records) | ++ | – | – | – | – | – | – | |
USA | Duke University Eye Center (active disease registry) | +++ | +++ | +++ | +++ | +++ | +++ | ++ |
Bascom Palmer Eye Institute (active disease registry) | ++ | +++ | +++ | +++ | +++ | – | – | |
IMS Health (administrative/claims database) | ++ | – | +++ | +++ | +++ | – | +++ | |
Wilmer Eye Institute (electronic medical records) | ++ | +++ | +++ | +++ | +++ | – | – | |
Doheny Eye Institute (active disease registry) | +++ | +++ | +++ | +++ | – | – | – | |
VRMNY (electronic medical records) | +++ | +++ | +++ | +++ | – | – | – | |
Wills Eye Hospital (electronic medical records) | +++ | +++ | +++ | +++ | – | – | – | |
A2ASDOCT (prospective observational study) | +++ | +++ | +++ | – | – | – | – | |
Shiley Eye Center (prospective observational study) | ++ | +++ | +++ | +++ | – | ++ | ++ | |
BRFSS (questionnaire/survey) | +++ | – | + | – | – | ++ | ++ | |
i3 InVision Data Mart (electronic medical records) | +++ | – | ++ | +++ | – | – | – | |
New England Eye Center (retrospective observational study) | ++ | +++ | +++ | – | – | – | – | |
SOF/IAMD (prospective observational study) | +++ | +++ | + | + | – | – | – | |
Beaver Dam Eye Study (prospective observational study) | +++ | +++ | + | – | – | – | – | |
LALES (prospective observational study) | +++ | – | + | – | – | +++ | – | |
Nurses’ Health Study (prospective observational study) | +++ | – | ++ | + | – | – | – | |
CAREDS (prospective observational study) | +++ | – | + | – | – | – | – | |
MESA | +++ | – | + | – | – | – | – | |
NHANES | +++ | – | + | – | – | – | – | |