Fig. 2

Fundus photographs (a, d, g), structural en face SS-OCT images (b, e, h), SS-OCT-A images (c, f, i), and SS-OCT B-scans (j, k, l) during the course of treatment. At 4 weeks after treatment, a. Vitreous haze decreased, but yellow-white infiltrate remained near the foveal center. b. Many collateral vascular branches surrounding the lesion (white arrows) and diffuse choroidal dilation, which is more remarkable in magnified image (Box 1) are shown. c. SS-OCT-A image showed congested choroidal vasculature. d, e, f. After two intravitreal injections of clindamycin, the size of macular infiltrates decreased with more discrete margins. g. After 3.5 months of additional treatment, the macular lesion changed to chorioretinal scar. h, i. Normalization of dilated choroidal vessels and constriction of collateral branch vessels around the lesion (white arrows), which is more remarkable in magnified image (Box 2) are seen. j. An SS-OCT B-scan through the lesion (white line on the fundus photograph) demonstrated disruption of the neurosensory retina, interruption of the photoreceptor inner and outer segment junction and RPE elevation. Multiple hyperreflective dots in the vitreous cavity indicating severe vitritis (white arrows), thickened posterior hyaloid (white arrowheads), and dilated Haller’s layer vessels (white asterisks) were also noted. k. The choroidal thickness decreased further. l. Atrophic retinal thinning, overlying thickened posterior hyaloid (white arrowheads), and pronounced choroidal thinning are seen