Table 1 Baseline epidemiology, predisposing factors and clinical characteristics of fungal keratitis according to prior topical steroid use
Characteristics | PS (n = 30) | NPS (n = 53) | p-value |
|---|---|---|---|
Epidemiology | |||
 Male sex | 19 (63.3) | 29 (54.7) | 0.445 |
 Age, years | 60.2 ± 14.9 | 64.6 ± 13.9 | 0.180 |
 Occupation | |||
  Agriculture | 14 (46.7) | 25 (47.2) | 0.965 |
  Non-agriculture | 16 (53.3) | 28 (52.8) |  |
 Symptom duration, days | 19.7 ± 15.4 | 15.0 ± 13.8 | 0.154 |
  Median (range) | 14 (2–150) | 10 (1–90) | 0.127†|
 Referral from primary eye clinic | 11 (36.7) | 4 (7.5) | 0.001 |
Predisposing factors | |||
 Corneal trauma | 21 (70.0) | 43 (81.1) | 0.246 |
  Vegetable matter or wood | 8 (26.7) | 21 (39.6) | 0.234 |
  Soil or water | 9 (30.0) | 16 (30.2) | 0.986 |
  Other trauma | 4 (13.3) | 6 (11.3) | 1.000* |
 Previous OSD | 13 (43.3) | 12 (22.6) | 0.048 |
  Herpetic keratitis | 7 (23.3) | 5 (9.4) | 0.108* |
  Punctate keratopathy | 3 (10.0) | 2 (3.8) | 0.346* |
  Old corneal opacity | 2 (6.7) | 3 (5.7) | 1.000* |
  Other keratopathya | 1 (3.3) | 2 (3.8) | 1.000* |
 Contact lens wear | 1 (3.3) | 4 (7.5) | 0.649* |
 Previous ocular surgery | 10 (33.3) | 10 (18.9) | 0.139 |
 Systemic disease | 12 (40.0) | 21 (39.6) | 0.973 |
  Diabetes mellitus | 4 (13.3) | 10 (18.9) | 0.518 |
  Hypertension | 7 (23.3) | 12 (22.6) | 0.943 |
Initial clinical characteristics | |||
 Central corneal lesion | 22 (73.3) | 42 (79.2) | 0.538 |
 Epithelial defect size (mm2) | 12.7 ± 12.4 | 10.5 ± 11.2 | 0.404 |
   ≥ 10 mm2 | 13 (43.3) | 16 (30.2) | 0.228 |
 Depth of infiltration | |||
  Superficial (0–50%) | 14 (46.7) | 36 (67.9) | 0.057 |
  Deep (50–100%) | 16 (53.3) | 17 (32.1) |  |
 Hypopyon | 9 (30.0) | 17 (32.1) | 0.845 |
 Presenting BCVA (logMAR) | 1.63 ± 0.96 | 1.47 ± 1.14 | 0.486 |
   < 0.1, Snellen | 20 (66.7) | 27 (51.9) | 0.194 |