Fig. 2

Changes in external limiting membrane (ELM) and ellipsoid zone (EZ) defects after MH surgery using the ILM insertion technique with NGF injection (solid circles) or ILM insertion alone (solid squares). The mean ELM and EZ defect sizes decreased significantly at 1st, 3rd, and 6th months after surgery in both groups (ELM: P < 0.0001, < 0.0001, and < 0.0001, =0.0008, < 0.0001, and < 0.0001, respectively, compared to baseline; EZ: P < 0.0001, < 0.0001, and < 0.0001, =0.0031, < 0.0001, and < 0.0001, respectively, compared to baseline). Defect resolution was significantly better in the NGF than the insertion group (P = 0.0465 and 0.0464 for ELM and EZ, respectively). The error bars indicate SEMs. *P < 0.05 for the comparison between the two groups