cytokines | nAMD (pg/ml) | PCV (pg/ml) | Control (pg/ml) | P value (nAMD vs Control) | P value (PCV vs Control) | P value (nAMD vs PCV) |
---|---|---|---|---|---|---|
BDNF | 4.58 ± 2.90 | 4.82 ± 2.83 | 18.69 ± 4.58 | < 0.0001 | < 0.0001 | 0.846 |
EGF | 4.34 ± 2.65 | 4.07 ± 3.29 | 5.36 ± 2.72 | 0.403 | 0.208 | 0.807 |
Eotaxin | 20.09 ± 3.96 | 17.64 ± 5.64 | 18.42 ± 6.03 | 0.449 | 0.671 | 0.221 |
GMCSF | 31.62 ± 18.47 | 20.04 ± 17.93 | 40.07 ± 11.66 | 0.211 | 0.001 | 0.061 |
HGF | 238.12 ± 113.63 | 325.59 ± 191.52 | 624.95 ± 165.93 | < 0.0001 | < 0.0001 | 0.165 |
IL-1RA | 99.54 ± 31.25 | 89.35 ± 38.98 | 96.04 ± 37.40 | 0.815 | 0.593 | 0.453 |
IP-10 | 49.57 ± 36.70 | 33.44 ± 29.05 | 100.99 ± 38.55 | < 0.0001 | < 0.0001 | 0.195 |
MCP-1 | 61.57 ± 43.04 | 91.56 ± 88.82 | 274.24 ± 63.01 | < 0.0001 | < 0.0001 | 0.271 |
MIP-1α | 8.91 ± 4.55 | 8.94 ± 5.46 | 8.72 ± 5.48 | 0.930 | 0.900 | 0.985 |
MIP-1β | 50.91 ± 10.24 | 53.34 ± 17.27 | 55.47 ± 12.22 | 0.443 | 0.667 | 0.650 |
IL-2 | 0.32 ± 0.24 | 0.31 ± 0.24 | 0.32 ± 0.25 | 0.993 | 0.948 | 0.943 |
IL-4 | 0.03 ± 0.01 | 0.03 ± 0.01 | 0.03 ± 0.01 | 0.755 | 0.766 | 0.944 |
IL-5 | 0.07 ± 0.06 | 0.09 ± 0.05 | 0.08 ± 0.05 | 0.559 | 0.386 | 0.151 |
IL-6 | 0.72 ± 0.55 | 0.79 ± 0.48 | 0.96 ± 0.53 | 0.259 | 0.327 | 0.728 |
IL-8* | 40.68 ± 35.47 | 14.63 ± 29.94 | 0.58 ± 0.60 | 0.053 | 0.012 | 0.012 |
IL-12p70* | 2.89 ± 1.99 | 1.17 ± 1.67 | 3.49 ± 0.34 | 0.236 | < 0.0001 | 0.029 |
IL-13 | 1.36 ± 1.26 | 2.25 ± 1.62 | 6.40 ± 1.58 | < 0.0001 | < 0.0001 | 0.120 |
IL-15 | 0.02 ± 0.01 | 0.02 ± 0.01 | 0.02 ± 0.01 | 0.553 | 0.835 | 0.642 |
IL-17A* | 1.05 ± 0.60 | 1.30 ± 0.84 | 2.27 ± 1.65 | 0.008 | 0.008 | 0.370 |
IL-18* | 40.98 ± 32.69 | 51.18 ± 37.16 | 0.41 ± 0.32 | < 0.0001 | < 0.0001 | 0.938 |
IL-21* | 22.30 ± 20.41 | 14.78 ± 16.20 | 0.00 ± 0.00 | < 0.0001 | < 0.0001 | 0.243 |
IL-23 | 0.05 ± 0.02 | 0.03 ± 0.02 | 0.04 ± 0.03 | 0.622 | 0.182 | 0.078 |
IL-27 | 0.04 ± 0.03 | 0.05 ± 0.03 | 0.05 ± 0.03 | 0.802 | 0.980 | 0.764 |
IL-31* | 10.11 ± 6.34 | 8.83 ± 5.13 | 0.17 ± 0.49 | < 0.0001 | < 0.0001 | 0.559 |
LIF* | 87.17 ± 8.54 | 74.76 ± 36.89 | 14.33 ± 5.15 | < 0.0001 | < 0.0001 | 0.508 |
NGFβ | 11.10 ± 6.64 | 9.78 ± 6.55 | 8.82 ± 5.09 | 0.365 | 0.646 | 0.562 |
PDGF-BB | 1.90 ± 0.77 | 1.68 ± 0.88 | 1.62 ± 0.90 | 0.426 | 0.845 | 0.482 |
PIGF | 0.28 ± 0.20 | 0.25 ± 0.14 | 0.26 ± 0.14 | 0.806 | 0.852 | 0.657 |
RANTES | 4.49 ± 3.74 | 6.65 ± 4.26 | 4.23 ± 3.17 | 0.873 | 0.070 | 0.132 |
SCF* | 5.75 ± 3.34 | 23.66 ± 3.34 | 5.89 ± 3.92 | 0.947 | 0.041 | 0.185 |
SDF1-α* | 285.56 ± 73.64 | 273.10 ± 135.54 | 41.10 ± 10.58 | < 0.0001 | < 0.0001 | 0.755 |
FGF-basic* | 0.11 ± 0.14 | 0.05 ± 0.10 | 0.00 ± 0.00 | < 0.0001 | 0.001 | 0.031 |
VEGF-A* | 175.71 ± 36.29 | 154.43 ± 87.56 | 38.69 ± 17.26 | < 0.0001 | < 0.0001 | 0.483 |
VEGF-D* | 242.49 ± 28.96 | 221.50 ± 96.24 | 43.66 ± 23.61 | < 0.0001 | < 0.0001 | 0.459 |