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Fig. 4 | BMC Ophthalmology

Fig. 4

From: Longitudinal observation of OCT imaging is a valuable tool to monitor primary vitreoretinal lymphoma treated with intravitreal injections of methotrexate

Fig. 4

Changes of PVRL features evidenced by SD-OCT. Changes of OR fuzzy borders in OD of case 5 (a-d). Before treatment, OR fuzzy borders and intraretinal infiltration were observed (a). After induction treatment, OR fuzzy borders were significantly reduced (b). After consolidation treatment, OR fuzzy borders further reduced (c). One month post maintenance treatment, OR fuzzy borders were resolved. In the nasal, the outer retina returned to almost normal, while in the temporal, disruption of the outer retina was observed (d). Changes of PED in OS of case 7 (e-h). Before treatment, PED and OR fuzzy borders were observed (e). After induction treatment, PED disappeared (f). After consolidation treatment, OR fuzzy borders further reduced (g). One month post maintenance treatment, the outer retina returned to normal (h). Changes of subretinal infiltration in OS of case 3 (i-l). Before treatment, subretinal infiltration and OR fuzzy borders were observed (i). After induction treatment, subretinal infiltration was absorbed (j). After consolidation treatment, OR fuzzy borders further reduced (k). One month post maintenance treatment, the outer retina returned to almost normal (l). Changes of intraretinal infiltration in OD of case 3 (m-p). Before treatment, OCT disclosing broad intraretinal hyperreflective infiltration (m). Post induction treatment, intraretinal infiltration reduced greatly (n). Post consolidation treatment, intraretinal infiltration further reduced (o). One month post maintenance treatment, thinning of the inner retina and disruption of outer of retina were observed in the temporal. And other lesions were absorbed and retina returned to normal (p). Changes of SRF in the right eye of case 6 (q-t). Before treatment, OCT disclosing SRF, intraretinal infiltration, subretinal infiltration and OR fuzzy borders (q). After induction treatment, SRF was absorbed, subretinal deposits appeared (r). After consolidation treatment, hyperreflective infiltration further reduced (s). One month post maintenance treatment, atrophy of the retina was observed (t)

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BMC Ophthalmology

ISSN: 1471-2415

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