Characteristics of diffuse retinal nerve fiber layer defects in red-free photographs as observed in optical coherence tomography en face images

Table 1 Demographics of open-angle glaucoma patients

	No defect (n = 25)	Localized defect (n = 106)	Diffuse defect (n = 78)	P value*
Age (yrs)	63.96 ± 13.78	56.99 ± 13.31	56.63 ± 13.82	0.029
Number of female patients (%)	12 (48.0)	44 (41.5)	26 (33.3)	0.337^†
Laterality (Right: Left)	10:15	57:49	37:41	0.406^†
Diagnosis (%)				0.079^†
NTG	15 (60.0)	45 (42.5)	27 (34.6)
POAG	10 (40.0)	61 (57.5)	51 (65.4)
Baseline IOP (mmHg)	16.1 ± 4.1	16.5 ± 3.6	18.7 ± 8.6	0.386
IOP (mmHg)	13.1 ± 3.1	13.6 ± 2.4	13.8 ± 3.0	0.674
SE (diopters)	−0.26 ± 3.41	−2.48 ± 4.41	− 2.16 ± 3.66	<0.001
CCT (μm)	538.61 ± 54.25	537.22 ± 35.77	532.50 ± 34.10	0.508
AXL (mm)	24.60 ± 2.11	25.11 ± 1.83	24.99 ± 2.19	0.492
MD (dB)	−4.50 ± 5.88	− 7.52 ± 6.72	−13.21 ± 8.74	<0.001
PSD (dB)	3.44 ± 2.22	7.41 ± 4.24	9.06 ± 4.50	<0.001
VFI (%)	92.31 ± 6.97	77.52 ± 21 .51	61.83 ± 24.72	<0.001

*Kruskal-Wallis Test, ^†Pearson’s chi-square test
NTG Normal-tension glaucoma, POAG Primary open-angle glaucoma, IOP Intraocular pressure, SE Spherical equivalent, CCT Central corneal thickness, AXL Axial length, MD Mean deviation, PSD Pattern standard deviation

ISSN: 1471-2415