Fig. 1

Age and Sex Boxplots. a Presenting ages of the 2913 patients in cohorts of 20 years. The boxes indicate 25th, 50th and 75th percentile of the age distributions. The red + represents a 91 year old female outlier. The inset shows a histogram of all the ages. A bootstrap analysis showed that overall the females presented significantly earlier than males in most cohorts. b In the overall distribution of ages females presented earlier than males at the 25th, 50th and 75th percentiles