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Table 4 Visual and Anatomical Outcomes after 18 Months of Treatment with Aflibercept for Central Retinal Vein Occlusion, Stratified with Respect of Injection Interval at 18 Months

From: A treat and extend protocol with Aflibercept for cystoid macular oedema secondary to central retinal vein occlusion – an 18-month prospective cohort study

 

Injection interval ″ 8 weeks

Injection interval ≥ 10 weeks

P value

Absolute visual acuity (ETDRS letters)

75.8 ± 11.5

73.8 ± 9.3

0.70

Mean gain in visual acuity (ETDRS letters)

22.8 ± 20.3

21.2 ± 11.6

0.85

Gain in visual acuity by ≥15 ETDRS letters

5 of 8 (63%)

7 of 9 (78%)

0.62

Absolute central macular thickness (μm)

262 [242 to 285]

272 [275 to 296]

0.54

Mean reduction in central macular thickness (μm)

− 552 ± 325

− 518 ± 296

0.83

  1. ETDRS Early Treatment of Diabetic Retinopathy Study