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Table 3 Vessel density (VD) (Mean ± SD) of macular deep plexus at baseline and 1 day/1 week/1 month after FS-LASIK

From: Microvascular changes in macula and optic nerve head after femtosecond laser-assisted LASIK: an optical coherence tomography angiography study

 

Baseline

(mean ± SD) %

1 day

(mean ± SD) %

1 week

(mean ± SD) %

1 month

(mean ± SD) %

Whole area (6*6mm2)

52.95 ± 0.74

49.64 ± 0.81*

50.46 ± 0.91*

51.4 ± 0.81

Fovea Region

38.22 ± 1.17

36.14 ± 1.19*

36.21 ± 1.2*

36.35 ± 1.17*

Parafovea Region

58.27 ± 0.49

55.56 ± 0.56*

55.91 ± 0.8*

56.93 ± 0.54*

Perifovea Region

54.14 ± 0.83

50.59 ± 0.91*

51.67 ± 1.01*

52.63 ± 0.9

  1. VD at baseline was compared with VD at 1 day/1 week/1 month respectively using the repeated-measures analysis. The VD of whole area of DPC significantly differ after surgery (F(3,132) = 4.45, P = 0.005). Vessel density was decreased 1 day after surgery (P = 0.001, P = 0.022 at 1 week and 1 month respectively) and gradually recovered to its normal range in 1 month (P = 0.102). The preoperative VD of fovea region was significantly difference from the VD at 1 day/1 week/1 month after surgery (F = (3132) = 11.73, P < 0.001). VD at 1 day/1 week/1 month after surgery decreased significantly (P < 0.001). VD of parafovea region significantly changed after surgery (F(2.71,119.26) = 5.13,P = 0.003). Vessel density of parafovea region was decreased after surgery (P < 0.001, P = 0.01, P = 0.039 at 1 day/1 week/1 month respectively). The perifovea region also changed postoperatively (F(3,132) = 4.09,P = 0.008). the vessel density was decreased at 1 day (P = 0.001) and gradually returned to its preoperatively level in 1 month (P = 0.04, P = 0.142 at 1 week and 1 month respectively). * represented P < 0.05