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Fig. 3 | BMC Ophthalmology

Fig. 3

From: Ripasudil alleviated the inflammation of RPE cells by targeting the miR-136-5p/ROCK/NLRP3 pathway

Fig. 3

Suppression of miR-136-5p lead to the upregulation of inflammatory factors and increasing apoptosis ratios. a The levels of TNF-α, IL-6 and MCP-1 in the supernatant were measured with the ELISA assays. b The apoptosis rates of RPE cells were determined with the flow cytometry. c The quantitative data of apoptosis rates. d The expression of apoptosis-related proteins (Bax, Bcl-2, Caspase3, Cleaved caspase3, Caspase9 and Cleaved caspase9) in RPE cells was detected with western-blotting. *p < 0.05, **p < 0.01, ***p < 0.001

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