Aqueous humour cytokines profiles in eyes with Coats disease and the association with the severity of the disease

BMC Ophthalmology

Table 3 Association of aqueous humour cytokine concentrations with the extent of retinal exudation and exudative retinal detachment

Cytokines	Retinal exudation		Exudative retinal detachment
Cytokines	r	P-Value^#	r	P-Value^#
VEGF	0.563	< 0.001	0.544	0.001
IL-6	0.338	0.051	0.607	< 0.001
IL-8	0.749	< 0.001	0.775	< 0.001
MCP-1	0.546	0.001	0.642	< 0.001
MIP-1α	0.753	< 0.001	0.562	< 0.001
IP-10	0.417	0.011	0.328	0.051
VCAM-1	0.284	0.099	0.280	0.103
ICAM-1	0.401	0.019	0.309	0.076

Values in bold font are statistically significant at P < 0.05
VEGF vascular endothelial growth factor, IL interleukin, MCP-1 monocyte chemoattractant protein-1, MIP-1α macrophage inflammatory protein-1α, IP-10 interferon-γ-inducible protein-10, VCAM vascular cell adhesion molecule, ICAM intercellular cell adhesion molecule
^# Spearman’s correlation test was used to determine the association of cytokine concentrations with the extent of retinal exudation and exudative retinal detachment

ISSN: 1471-2415