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Table 3 Preoperative, three-month postoperative, and magnitude of surgically-induced corneal HOAs

From: Comparison of outcomes after topography-modified refraction versus wavefront-optimized versus manifest topography-guided LASIK

Parameter (Mean RMS value ± SD, μm) WFO Manifest TG TMR P-value Post hoc (P-value)
Preoperative HOAs
 Total HOAs 0.41 ± 0.16 0.46 ± 0.20 0.44 ± 0.14 .201  
 Coma 0.19 ± 0.09 0.22 ± 0.13 0.20 ± 0.11 .372  
 Trefoil 0.15 ± 0.09 0.15 ± 0.10 0.14 ± 0.08 .791  
 Spherical aberration 0.15 ± 0.06 0.13 ± 0.06 0.14 ± 0.06 .158  
Three months postoperative HOAs
 Total HOAs 0.76 ± 0.38 0.60 ± 0.30 0.55 ± 0.19 .000* TMR < WFO (< .001), Manifest TG < WFO (.022)
 Coma 0.37 ± 0.25 0.26 ± 0.18 0.24 ± 0.14 .000* TMR < WFO (< .001), Manifest TG < WFO (.031)
 Trefoil 0.16 ± 0.09 0.14 ± 0.09 0.12 ± 0.10 .040* TMR < WFO (.034)
 Spherical aberration 0.36 ± 0.25 0.31 ± 0.22 0.23 ± 0.16 .002* TMR < WFO (.002)
Magnitude of surgically-induced HOAs
 Total HOAs 0.37 ± 0.41 0.14 ± 0.41 0.12 ± 0.25 .000* TMR < WFO (< .001), Manifest TG < WFO (.006)
 Coma 0.18 ± 0.26 0.05 ± 0.23 0.04 ± 0.18 .001* TMR < WFO (.001), Manifest TG < WFO (.010)
 Trefoil 0.01 ± 0.10 − 0.01 ± 0.09 − 0.02 ± 0.12 .233  
 Spherical aberration 0.21 ± 0.25 0.19 ± 0.25 0.09 ± 0.17 .004* TMR < WFO (.005)
  1. HOAs = higher-order aberrations; RMS = root mean square; WFO = wavefront-optimized; TG = manifest topography-guided; TMR = topography-modified refraction. *Statistically significant (P < .05)