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Table 4 Subgroup analysis of the TMR group

From: Comparison of outcomes after topography-modified refraction versus wavefront-optimized versus manifest topography-guided LASIK

Parameter (Mean ± SD)

Subgroup 1 (CA < RA)

Subgroup 2 (CA > RA)

P value

Preoperative

 BCVA (logMAR)

−0.07 ± 0.07

−0.07 ± 0.06

.843

 Sphere (D)

−2.55 ± 3.57

− 3.74 ± 1.75

.210

 Cylinder (RA; D)

−1.48 ± 0.69

−1.00 ± 0.66

.009*

 MRSE (D)

− 3.29 ± 3.69

− 4.24 ± 1.77

.330

 Flat keratometry (D)

42.95 ± 1.29

42.57 ± 1.20

.260

 Steep keratometry (D)

44.09 ± 1.45

43.99 ± 1.30

.780

 CA (D)

1.14 ± 0.62

1.42 ± 0.63

.111

 Magnitude difference between CA and RA (D)

− 0.34 ± 019

0.43 ± 0.27

.000*

 Axis difference between CA and RA (°)

19.3 ± 11.1

25.4 ± 16.3

.230

Postoperative 3 months

 UDVA (logMAR)

− 0.03 ± 0.11

−0.05 ± 0.11

.415

 UDVA (% of logMAR 0.0 or better)

68.8

82.6

.296

 Sphere (D)

0.14 ± 0.79

−0.01 ± 0.66

.440

 Cylinder (D)

−0.52 ± 0.23

−0.44 ± 0.37

.297

 MRSE (D)

−0.12 ± 0.80

−0.23 ± 0.67

.571

 MRSE (% of D within ±0.5)

68.8

68.1

.999

 MRSE (% of D within ±1.0)

93.8

91.3

.999

Change in astigmatism based on the Alpins method of vector analysis

 TIA

1.48 ± 0.69

1.09 ± 0.60

.027*

 SIA

1.52 ± 0.61

1.37 ± 0.78

.470

 DV

0.52 ± 0.23

0.46 ± 0.37

.568

 ME

0.04 ± 0.38

0.28 ± 0.38

.027*

 CI

1.16 ± 0.52

1.30 ± 0.51

.315

 IOS

0.47 ± 0.39

0.55 ± 0.54

.591

  1. TMR = topography-modified refraction; CA = corneal astigmatism; RA = refractive astigmatism; BCVA = best-corrected distance visual acuity; logMAR = logarithm of the minimal angle of resolution; MRSE = manifest refraction spherical equivalent; UDVA = uncorrected distance visual acuity; TIA = target-induced astigmatism; SIA = surgically-induced astigmatism; DV = difference vector; ME = magnitude of error; CI = correction index; IOS = index of success. *Statistically significant (P < .05)