Comparison of outcomes after topography-modified refraction versus wavefront-optimized versus manifest topography-guided LASIK

Table 5 Multivariable linear regression analysis of parameters with statistically significant association with ME on univariable analysis in the TMR group

Parameter	Value	Coefficient	95% CI	p-value
Preoperative CA (D)
Univariable analysis	1.37 ± 0.63	0.149	0.012–0.285	0.036*
Multivariable analysis	1.37 ± 0.63	−0.003	−0.106 – 0.099	0.950
Preoperative magnitude difference between CA and RA (D)
Univariable analysis	0.33 ± 0.39	0.392	0.187–0.597	< 0.001*
Multivariable analysis	0.33 ± 0.39	0.262	0.102–0.422	0.002*
Postoperative cylinder (D)
Univariable analysis	−0.45 ± 0.35	− 0.728	− 0.920 – − 0.536	< 0.001*
Multivariable analysis	−0.45 ± 0.35	− 0.677	− 0.855 – − 0.498	< 0.001*

ME = magnitude of error; TMR = topography-modified refraction; CA = corneal astigmatism; RA = refractive astigmatism. *Statistically significant (P < .05)

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