From: The findings of corneal specular microscopy in patients with type-2 diabetes mellitus
Without DR (n: 68) | Background DR (n:56) | Proliferative DR (n:71) | P1 | P2 | P3 | |
---|---|---|---|---|---|---|
Gender (M/F) | 28/40 | 24/32 | 35/36 | 0.56 | 0.14 | 0.24 |
Age (years) | 61.50 ± 7.791 | 63.77 ± 8.17 | 62.37 ± 7.07 | 0.145 | 0.124 | 0.247 |
Diabetes duration (years) | 5.32 ± 2.06 | 9.07 ± 3.92 | 13.25 ± 4.33 | 0.001 | 0.001 | 0.001 |
Fasting Blood Glucose (mg/dl) | 139.33 ± 36.50 | 189.53 ± 50.06 | 203.51 ± 57.91 | 0.001 | 0.001 | 0.004 |
Hemoglobin A 1c (%) | 7.02 ± 1.15 | 8.46 ± 1.41 | 9.13 ± 1.45 | 0.001 | 0.001 | 0.001 |
Blood urea nitrogen | 30.56 ± 9.11 | 39.81 ± 12.02 | 43.92 ± 13.97 | 0.001 | 0.001 | 0.001 |
Creatinine | 0.80 ± 0.27 | 1.01 ± 0.31 | 1.17 ± 0.26 | 0.001 | 0.001 | 0.001 |
Urine albumin-creatinine ratio (mg/g·Cre) | 9.87 ± 4.86 | 52.47 ± 42.72 | 113.30 ± 64.58 | 0.001 | 0.001 | 0.001 |
Endothelial Cell Density (cells/m2) | 2495.83 ± 365.39 | 2392.28 ± 462.73 | 2384.06 ± 432.98 | 0.043 | 0.021 | 0.872 |
Average cell size (μm2) | 403.22 ± 64.22 | 446.92 ± 79.08 | 452.16 ± 62.11 | 0.012 | 0.009 | 0.308 |
Coefficient of Variation (%) | 30.04 ± 5.29 | 31.34 ± 5.46 | 33.58 ± 5.58 | 0.044 | 0.004 | 0.408 |
Hexagonal cell ratio (%) | 66.16 ± 6.43 | 65.20 ± 5.80 | 64.60 ± 7.84 | 0.437 | 0.412 | 0.116 |
Central corneal thickness (μ) | 536.29 ± 51.68 | 538.84 ± 34.52 | 541.99 ± 33.21 | 0.467 | 0.278 | 0.654 |