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Fig. 5 | BMC Ophthalmology

Fig. 5

From: MicroRNA-182-5p protects human lens epithelial cells against oxidative stress-induced apoptosis by inhibiting NOX4 and p38 MAPK signalling

Fig. 5

MiR-182-5p binds NOX4 directly. A. Putative miR-182-5p binding site in the 3’UTR region of NOX4. B. Luciferase activity of cells transfected with NOX4-WT, NOX4-MUT, mimics control and miR-182-5p mimics. ** P < 0.01 vs. NOX4-WT+ mimics NC group. C. The expression of NOX4 protein regulated by upregulated or downregulated miR-182-5p. ** P < 0.01 vs. mimics NC group, ## P < 0.01 vs. inhibitor NC group. Independent experiments were carried out three times for each assay

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