Safety and efficacy of ripasudil in Japanese patients with glaucoma or ocular hypertension: 12-month interim analysis of ROCK-J, a post-marketing surveillance study

Table 3 Allergy and/or inflammation-related adverse drug reactions during ripasudil treatment

Allergy and/or inflammation-related ADRs, n (%)	N = 3359
No. of pts. with allergy and/or inflammation-related ADR	388 (11.6)
Blepharitis^a	189 (5.6)
Conjunctivitis^b	141 (4.2)
Eye pruritus	44 (1.3)
Punctate keratitis	25 (0.7)
Eyelid edema	9 (0.3)
Corneal erosion	9 (0.3)
Dermatitis contact	6 (0.2)
Erythema of eyelid	4 (0.1)
Corneal disorder	4 (0.1)
Dermatitis allergic	3 (0.1)
Conjunctival follicles	3 (0.1)
Eyelids pruritus	3 (0.1)
Keratitis	2 (0.1)
Other^c (incidence of each)	1 (< 0.1)

ADR adverse drug reaction, pts patients
^a Including blepharitis allergic
^b Including conjunctivitis allergic
^c One patient each developed conjunctival erosion, conjunctival edema, corneal epithelium defect, eczema eyelids, allergic keratitis

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