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Table 1 Baseline characteristics

From: Persistence and treatment patterns of fixed combination drugs for glaucoma: a retrospective claims database study in Japan

Characteristic

Fixed combination n = 364

Unfixed combination n = 1039

Overall

N = 1403

Age, mean (SD)

49.62 (10.72)

49.76 (10.03)

49.72 (10.21)

Age, n (%)

 20–34 years

26 (7.14)

72 (6.93)

98 (6.99)

 35–49 years

169 (46.43)

454 (43.70)

623 (44.40)

 50–64 years

137 (37.64)

448 (43.12)

585 (41.70)

  ≥ 65 years

32 (8.79)

65 (6.26)

97 (6.91)

Gender, n (%)

 Male

215 (59.07)

594 (57.17)

809 (57.66)

 Female

149 (40.93)

445 (42.83)

594 (42.34)

Systolic blood pressure, mmHg, mean (SD)

122.4 (15.77)

n = 251

124.76 (17.06)

n = 788

124.19 (16.78)

n = 1039

Diastolic blood pressure, mmHg, mean (SD)

76.28 (11.57)

76.72 (11.58)

76.62 (11.57)

Smoking status, n (%)

 Non-smoker

188 (51.65)

555 (53.42)

743 (52.96)

 Current smoker

53 (14.56)

140 (13.47)

193 (13.76)

 Missing/unknown

123 (33.79)

344 (33.11)

467 (33.29)

Type of glaucoma (ICD-10 code), n (%)

 Glaucoma suspect (H40.0)

85 (23.35)

278 (26.76)

363 (25.87)

 Primary open-angle glaucoma (H40.1)

57 (15.66)

231 (22.23)

288 (20.53)

 Glaucoma secondary to eye inflammation (H40.4)

3 (0.82)

4 (0.38)

7 (0.5)

 Glaucoma secondary to other eye disorders (H40.5)

21 (5.77)

27 (2.60)

48 (3.42)

 Glaucoma secondary to drugs (H40.6)

1 (0.27)

6 (0.58)

7 (0.5)

 Unspecified glaucoma (H40.9)

197 (54.12)

493 (47.45)

690 (49.18)

Hospital size, n (%)

  ≤ 19 hospital beds

235 (64.56)

741 (71.32)

976 (69.57)

 20–99 hospital beds

9 (2.47)

23 (2.21)

32 (2.28)

 100–199 hospital beds

8 (2.2)

21 (2.02)

29 (2.07)

 200–299 hospital beds

10 (2.75)

25 (2.41)

35 (2.49)

 300–499 hospital beds

22 (6.04)

54 (5.20)

76 (5.42)

  ≥ 500 hospital beds

80 (21.98)

175 (16.84)

255 (18.18)

Duration of second-line treatment (months), mean (SD)

13.4 (17.05)

12.25 (14.90)

12.55 (15.49)

  1. ICD International Classification of Diseases, N total number of patients, n number of patients, SD standard deviation