Skip to main content

Table 9 Comparative table of studies evaluating Pentacam topographic, pachymetric and aberrometry parameters in detecting subclinical (early) keratoconus (confusion matrix)

From: A predictive model for early diagnosis of keratoconus

Study Sensitivity (%) Specificity (%) AUC
BAD-Da [3]
 Ferreira-Mendes et al. [22] 68.40 84.60 0.839
 Huseynli et al. [9] 95.50 73.70 0.904
 Hashemi et al. [23] 81.10 73.20 0.860
 Shetty et al. [24] 83.80 86.00 0.887
 Ruiseñor Vázquez et al. [25] 89.20 82.30 0.930
 Ambrósio et al. [26] 93.60 94.60 0.975
 Steinberg et al. [27] 65.80 65.80 0.712
 Muftuoglu et al. [28] 60.00 90.00 0.834
 Castro-Luna et al.b 75.00 96.34 0.930
 PPI-Avga [3]
 Cui et al. [29] 94.70 89.70 0.957
 Huseynli et al. [9] 93.30 47.40 0.834
 Shetty et al. [24] 83.80 74.40 0.883
 Ruiseñor Vázquez et al. [25] 78.40 82.80 0.860
 Muftuoglu et al. [28] 77.00 65.00 0.806
 Steinberg et al. [27] 62.30 64.30 0.669
 Uçakhan et al. [30] 81.80 77.80 0.842
 Castro-Luna et al.b 75.00 90.24 0.850
IHDa [3]
 Kovács et al. [31] 80.00 75.00 0.880
 Bae et al. [32] 71.40 85.30 0.748
 Huseynli et al. [9] 82.30 65.00 0.782
 Shetty et al. [24] 43.20 67.40 0.627
 Uçakhan et al. [30] 75.00 60.30 0.703
 Castro-Luna et al.b 50.00 91.46 0.820
Art-MAXa [3]
 Kovács et al. [31] 84.00 54.00 0.740
 Shetty et al. [24] 86.50 69.80 0.850
 Muftuoglu et al. [28] 67.00 71.00 0.722
 Ruiseñor Vázquez et al. [25] 90.50 86.50 0.930
 Ambrósio et al. [26] 85.10 93.10 0.959
 Steinberg et al. [27] 30.80 30.60 0.272
 Castro-Luna et al.b 67.50 91.46 0.880
IVAa [3]
 Bae et al. [32] 71.40 61.80 0.733
 Huseynli et al. [9] 92.10 52.50 0.844
 Hashemi et al. [23] 82.30 73.20 0.860
 Shetty et al. [24] 10.80 95.30 0.609
 Uçakhan et al. [30] 86.40 61.90 0.768
 Castro-Luna et al.b 37.50 90.24 0.770
MCTa [3]
 Kovács et al. [31] 64.00 66.00 0.670
 Xu et al. [33] 92.00 47.00 0.695
 Cui et al. [29] 84.20 100.00 0.914
 Reddy et al. [34] 70.00 80.00 0.790
 Muftuoglu et al. [28] 64.00 58.00 0.652
 Uçakhan et al. [30] 88.90 61.40 0.805
 Steinberg et al. [27] 36.30 35.70 0.323
 Castro-Luna et al.b 45.00 87.80 0.780
Anterior coma to 90° [5]
 Heidari et al. [35] 75.00 100.00 0.857
 Castro-Luna et al.b 67.50 93.90 0.86
 Posterior coma to 90° [5]
 Heidari et al. [35] 75.00 78.6 0.813
 Castro-Luna et al.b 62.50 93.90 0.85
  1. aBAD-D: Belin/Ambrósio Enhanced Ectasia Display. PPI-Avg: Mean Pachymetry Progression Index IHD: index of height decentration Art-MAX: The Ambrósio relational thickness maximum, IVA: vertical asymmetry index, MCT: minimum corneal thickness. b own results