Fig. 4
From: Multimodal imaging features and genetic findings in Bietti crystalline dystrophy
Optical coherence tomography (OCT) and corresponding fundus fluorescein angiography (FFA) images of four patients with BCD. a-c FFA and OCT images of patient 1–3. FFA images show numerous hyperreflective spots of various configurations throughout the retina as well as the overlaid retinal vessels. The outer nuclear layer (ONL) is discontinuous in the macular region. Outer retinal tubulations (ORTs) confining to the ONL are shown (a-c, white arrows). Severe disruption of the ellipsoid zone/interdigitation zone and the RPE is shown in OCT image of patient 3 (c). d FFA and OCT images of patient 4 showing extensive degeneration of the retina and the RPE/choriocapillaris complex. A hyperreflective lesion associated with remarkable RPE elevation at the foveal center is shown (white arrow)