Table 2 Genotype and allele distribution of CFB (rs4151667) polymorphism among AMD patients and control group

Control

AMD

OR

P

AOR

P

Lower

Upper

Lower

Upper

Genotype^a

0.088

0.181

TT

166 (86.9%)

201 (93.1%)

Ref

Ref

AT

25 (13.1%)

14 (6.5%)

0.46

0.23

0.92

0.028

0.49

0.23

1.04

0.064

AA

0 (0.0%)

1 (0.5%)

–

–

–

–

–

–

–

–

Allele^b

T

357 (93.5%)

416 (96.3%)

Ref

Ref

A

25 (6.5%)

16 (3.7%)

0.55

0.29

1.04

0.068

0.63

0.31

1.26

0.191

Control

Wet

OR

95% CI

P

AOR

P

Lower

Upper

Lower

Upper

Genotype^a

0.146

0.320

TT

166 (86.9%)

164 (92.7%)

Ref

Ref

AT

25 (13.1%)

12 (6.8%)

0.49

0.24

1.00

0.050

0.55

0.26

1.19

0.131

AA

0 (0.0%)

1 (0.6%)

–

–

–

–

–

–

–

–

Allele^b

T

357 (93.5%)

340 (96.0%)

Ref

Ref

A

25 (6.5%)

14 (4.0%)

0.59

0.30

1.15

0.121

0.70

0.35

1.42

0.324

Control

Dry

OR

95% CI

P

AOR

95% CI

P

Lower

Upper

Lower

Upper

Genotype^a

0.176

0.149

TT

166 (86.9%)

37 (94.9%)

Ref

Ref

AT

25 (13.1%)

2 (5.1%)

0.36

0.08

1.58

0.176

1.20

1.12

1.28

0.000

AA

0 (0.0%)

0 (0.0%)

–

–

–

–

–

–

–

–

Allele^b

T

357 (93.5%)

76 (97.4%)

Ref

Ref

A

25 (6.5%)

2 (2.6%)

0.38

0.09

1.62

0.189

0.22

0.03

1.81

0.160

Dry

Wet

OR

P

AOR

P

Lower

Upper

Lower

Upper

Genotype^a

0.928

0.552

TT

37 (94.9%)

164 (92.7%)

Ref

Ref

AT

2 (5.1%)

12 (6.8%)

1.35

0.29

6.31

0.700

3.28

0.39

27.66

0.275

AA

0 (0.0%)

1 (0.6%)

–

–

–

–

–

–

–

–

Allele^b

T

76 (97.4%)

340 (96.0%)

Ref

Ref

A

2 (2.6%)

14 (4.0%)

1.56

0.35

7.03

0.559

3.21

0.39

26.39

0.278