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Table 1 Clinical and laboratory features of DR, DM and non-DM subjects

From: Plasma Ephrin-A1 level in a cohort of diabetic retinopathy patients

 

non-DM (n = 19)

DM (n = 16)

DR (n = 20)

P

P Value 1

P Value 2

P Value 3

Age (years)

60.53 ± 4.04

63.31 ± 4.97

60.25 ± 6.72

0.048

0.093

0.159

0.741

male/female

11/8

8/8

11/9

    

BMI (kg/m2)

22.01 ± 2.25

24.48 ± 3.17

24.32 ± 3.66

0.032

0.068

1

0.072

FPG (mmol/l)

5.57 ± 0.62

8.91 ± 3.04

8.16 ± 2.57

<0.001

<0.001

> 0.05

<0.001

HbA1c(%)

5.33 ± 0.32

8.65 ± 2.56

8.22 ± 1.84

<0.001

<0.001

> 0.05

<0.001

VEGF165(pg/ml)

34.79 ± 38.65

24.43 ± 17.33

40.91 ± 58.01

0.093

 

Ephrin-A1(ng/ml)

0.27 ± 0.13

0.35 ± 0.34

3.63 ± 4.63

<0.001

> 0.05

<0.001

<0.001

Serum creatinine (μg/ml)

54.32 ± 12.74

68.88 ± 34.04

70.10 ± 26.63

0.063

 

Total cholesterol (mmol/l)

5.19 ± 1.09

5.41 ± 1.45

5.00 ± 1.00

0.064

 

Duration of DM (months)

0

46 ± 18.5

118 ± 49

    
  1. P indicates P value of the three group; P Value 1 indicates Padj value of the non-DM group vs the DM group; P Value 2 indicates Padj value of the DM group vs the DR group; P Value 3 indicates Padj value of the non-DM group vs the DR group.
  2. BMI between the three groups was analyzed using one-way ANOVA. Age, HbA1c, FPG, serum creatinine, total cholesterol, ephrin-A1 and VEGF were analyzed by Kruskal-Wallis Test.
  3. The P values of serum creatinine, total cholesterol and VEGF were >0.05, suggesting that there was no statistical significance between the three groups. We found that the P values of age, HbA1c, fasting blood glucose and ephrin-A1 were >0.05, then Mann-Whitney U Test corrected by Bonferroni was further used for comparison between any two groups.
  4. FPG Fasting plasma glucose. Values are means ± SD