From: Topical citicoline and vitamin B12 versus placebo in the treatment of diabetes-related corneal nerve damage: a randomized double-blind controlled trial
Cit-B12
Placebo
P
Baseline
10.6 ± 2.9
12.7 ± 2.9
0.09
Month 4
13.4 ± 4.1*
15.8 ± 3.9*
0.07
Month 8
14.3 ± 4.1*
16.5 ± 2.9 *
0.08
Month 12
12.8 ± 4.1*
14.8 ± 3.0§
0.10
Month 18
14.2 ± 4.6*
14.4 ± 4.0^
0.43