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Table 2 Corneal FLD: percentage improvement vs baseline

From: Topical citicoline and vitamin B12 versus placebo in the treatment of diabetes-related corneal nerve damage: a randomized double-blind controlled trial

 

Cit-B12

Placebo

P

Month 4

27% ± 23% (+ 63%; − 14%)

26% ± 18% (+ 49%; − 2%)

0.43

Month 8

37% ± 27% (+ 94%; − 9%)

34% ± 30% (+ 98%; − 2%)

0.39

Month 12

21% ± 29% (+ 66%; − 44%)

19% ± 17% (+ 50%; − 4%)

0.40

Month 18

33% ± 26% (+ 88%; − 9%)

15% ± 25% (+ 42%; − 39%)

0.04