From: Lens-induced myopization and intraocular pressure in young guinea pigs
Study group, right eyes | Control group, right eyes | P-Value | Study group, Left eyes (no intervention) | Control group, left eyes (no intervention) | P-value | |
---|---|---|---|---|---|---|
Baseline | ||||||
IOP (mmHg) | 14.3 ± 2.6 | 15.0 ± 2.1 | 0.52 | 15.4 ± 3.4 | 15.4 ± 3.9 | 1.00 |
RE (D) | 1.83 ± 0.88 | 1.93 ± 0.66 | 0.78 | 1.75 ± 0.55 | 2.08 ± 0.55 | 0.21 |
AL (mm) | 7.99 ± 0.04 | 7.98 ± 0.07 | 0.61 | 7.98 ± 0.05 | 7.97 ± 0.05 | 0.76 |
Study end | ||||||
IOP (mmHg) | 12.2 ± 2.4 | 18.8 ± 3.6 | < 0.001 | 15.0 ± 3.3 | 16.0 ± 3.9 | 0.54 |
RE (D) | −1.65 ± 1.80 | −3.48 ± 2.06 | 0.049 | − 0.93 ± 2.05 | − 0.18 ± 1.08 | 0.32 |
Change in RE (D) | −3.48 ± 1.75 | −5.40 ± 2.38 | 0.055 | −2.68 ± 2.54 | −2.25 ± 1.16 | 0.64 |
AL (mm) | 8.61 ± 0.12 | 8.70 ± 0.06 | 0.038 | 8.51 ± 0.05 | 8.53 ± 0.10 | 0.70 |
Axial elongation (mm) | 0.62 ± 0.15 | 0.73 ± 0.09 | 0.07 | 0.53 ± 0.06 | 0.55 ± 0.12 | 0.62 |