Lens-induced myopization and intraocular pressure in young guinea pigs

BMC Ophthalmology

Table 2 Measurements (mean ± standard deviation) of guinea pigs at baseline and at study end

	Study group, right eyes	Study group, left eyes	P-Value	Control group, right eyes	Control group, left eyes	P-Value
IOP (mmHg)
Baseline	14.3 ± 2.6	15.4 ± 3.4	0.43	15.0 ± 2.1	15.4 ± 3.9	0.78
1 week	11.2 ± 1.9	16.4 ± 4.0	0.002	18.6 ± 4.0	15.2 ± 3.3	0.05
2 weeks	11.4 ± 1.9	17.1 ± 3.6	0.001	16.9 ± 5.0	14.5 ± 4.0	0.25
3 weeks	11.2 ± 1.5	17.0 ± 3.6	0.000	17.7 ± 4.7	16.3 ± 4.3	0.49
4 weeks	11.8 ± 1.8	15.3 ± 3.6	0.01	18.2 ± 4.4	15.0 ± 3.4	0.09
5 weeks	12.2 ± 2.4	15.0 ± 3.3	0.045	18.8 ± 3.6	16.0 ± 3.9	0.11
RE (D)
Baseline	1.83 ± 0.88	1.75 ± 0.55	0.82	1.93 ± 0.66	2.08 ± 0.55	0.59
1 week	0.98 ± 1.30	1.45 ± 0.63	0.31	1.23 ± 0.74	1.33 ± 0.41	0.71
2 weeks	0.18 ± 1.09	1.35 ± 0.41	0.008	0.35 ± 1.52	1.28 ± 0.43	0.09
3 weeks	− 0.38 ± 1.08	0.23 ± 1.30	0.28	− 1.60 ± 1.41	0.78 ± 0.85	< 0.001
4 weeks	−1.10 ± 1.53	− 0.40 ± 1.58	0.33	−2.48 ± 1.72	0.33 ± 1.02	0.001
5 weeks	−1.65 ± 1.80	− 0.93 ± 2.05	0.41	− 3.48 ± 2.06	−0.18 ± 1.08	0.001
AL (mm)
Baseline	7.99 ± 0.04	7.98 ± 0.05	0.63	7.98 ± 0.07	7.97 ± 0.05	0.89
1 week	8.08 ± 0.05	8.06 ± 0.04	0.28	8.09 ± 0.06	8.05 ± 0.05	0.18
2 weeks	8.20 ± 0.10	8.18 ± 0.05	0.68	8.26 ± 0.09	8.17 ± 0.06	0.02
3 weeks	8.38 ± 0.06	8.29 ± 0.06	0.005	8.42 ± 0.07	8.32 ± 0.10	0.02
4 weeks	8.48 ± 0.09	8.42 ± 0.06	0.09	8.55 ± 0.08	8.44 ± 0.08	0.007
5 weeks	8.61 ± 0.12	8.51 ± 0.05	0.03	8.70 ± 0.06	8.53 ± 0.10	0.000

IOP Intraocular pressure, RE Refractive error, D Diopters, AL Axial length. The P-values indicate the statistical significance of the difference between the two groups in the preceding two columns of the table

ISSN: 1471-2415