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Table 1 Comparison of the Demographic and Clinical Characteristics of Control,PPG, and POAG Eyes

From: Diagnostic ability of OCT parameters and retinal ganglion cells count in identification of glaucoma in myopic preperimetric eyes

Parameters

Control

PPG

POAG

P-value

P-value for t test between groups

     

Control vs PPG

Control vs POAG

PPG vs POAG

Eyes (n)

36

64

54

    

Age (y)

55.51 (7.72)

56.00 (7.28)

59.93 (7.28)

0.15*

0.82 ‡

0.06 ‡

0.18 ‡

Sex (M/F)

16/20

15/39

22/32

0.21

0.102 ‡

0.73 ‡

0.16 ‡

Refraction (D)

−2.53 (2.45)

−2.49 (2.65)

−3.24 (2.74)

0.29*

0.93 ‡

0.21 ‡

0.13 ‡

Axial lenght (mm)

24.18 (1.16)

24.28 (2.19)

24.99 (2.75)

0.03*

0.78 ‡

0.04 ‡

0.03 ‡

MD (dB)

−0.48 (0.83)

−0.59 (1.64)

−6.50 (6.74)

< .001*

0.73 ‡

< .001 ‡

< .001 ‡

PSD (dB)

1.63 (0.37)

1.75 (0.96)

6.30 (3.63)

< .001*

0.42‡

< .001 ‡

< .001 ‡

RNFLavg (μ)

108.22 (10.90)

93.70 (9.95)

80.24 (13.2)

< .001*

< .001 ‡

< .001 ‡

< .001 ‡

GCCavg (μ)

97.11 (6.46)

85.52 (7.32)

75.19 (10.95)

< .001*

< .001 ‡

< .001 ‡

< .001 ‡

Estimated total RGC count (n)

1,140,520.81 (138,535.47)

958,579.68 (150,472.40)

616,463.06 (226,325.70)

< .001*

< .001‡

< .001 ‡

< .001 ‡

  1. The parameters are expressed as mean and SD; MD Mean deviation of SAP, PSD Pattern standard deviation of SAP. RNFL Retinal Nerve Fiber Layer, GCC Ganglion Cell Complex, RGC Retinal Ganglion Cell
  2. *P-value for ANOVA, significant for p < 0.05
  3. P-value for χ2 test, significant for p < 0.05
  4. P-value for t test between groups, significant for p < α adjusted with Bonferroni correction (p-value with IC 95% / number of comparisons = 0.05/3 = 0.0167)