Fig. 4
From: Neurosarcoidosis presenting as CRVO combined CRAO: a biopsy-proven case report of a Chinese patient
The left optic nerve biopsy showing the optic nerve tissues. a: The normal structure of the optic nerve was disrupted with numerous non-caseating granulomas (haematoxylin-eosin (HE) stain, × 40). b: A giant cell with multiple nuclei is surrounded by a rim composed of lymphoid cells and fibrotic collagen (HE stain, × 400). Immunohistochemistry was negative for CD68 (c, × 200) and showed a loss of GFAP (d, × 40)