Fig. 1

Color fundus photographs and fluorescein angiograms at the onset of choroidal neovascularization (CNV). a: Color fundus photograph of the right eye shows many areas of patchy atrophies and Fuchs’ spots on a background of severe diffuse atrophy. b: Left eye shows many whitish lesions and retinal and subretinal hemorrhages. The hemorrhages on the superonasal side of the fovea are relatively large and botryoid-shaped (white arrow), and the hemorrhages in the parafoveal region are linear (dotted arrow). The hemorrhages on the inferotemporal side of the optic disc are small, flat, and round (black arrows). c: Early phase fluorescein angiogram showing that the areas of the retinal and subretinal hemorrhages are hypofluorescent at the early phase. There are also early hyperfluorescence within the area of the botryoidal-shaped hemorrhages (arrows). d: Late phase of fluorescein angiogram. During the entire phase, the areas corresponding to the retinal and subretinal hemorrhages are hypofluorescent due to blockage. It can also be seen that the late leakages within the area of the botryoidal-shaped hemorrhages (arrows) and adjacent to the linear retinal hemorrhages (arrowheads), which are suspected to be multiple developments of the CNV