Table 4 Visual function outcomes using some current commonly used endpoints: ROC analysis
Tests | AUC (SE) | AUC 95% CI | Youden Index | Sensitivity (%) at 80% Specificity |
|---|---|---|---|---|
ETDRS VA | 0.56 (0.08) | 0.41–0.71 | 0.11 | 27.15 |
ETDRS LL 2.0 ND VA | 0.51 (0.08) | 0.35–0.66 | 0.08 | 17.93 |
ETDRS LL 2.0 ND Deficit | 0.46 (0.08) | 0.31–0.61 | 0.10 | 8.12 |
MNREAD Regular Max reading speed (wpm) | 0.47 (0.08) | 0.31–0.63 | 0.14 | 22.73 |
MNREAD Regular Reading acuity | 0.62 (0.08) | 0.47–0.78 | 0.19 | 34.91 |
MNREAD LL 2.0 ND Max reading speed (wpm) | 0.36 (0.08) | 0.21–0.51 | 0.12 | 9.09 |
MNREAD LL 2.0 ND Reading acuity | 0.48 (0.08) | 0.33–0.64 | 0.01 | 16.82 |
Pelli-Robson CS | 0.63 (0.07) | 0.48–0.77 | 0.20 | 36.78 |