Table 2 Aqueous cytokine concentrations in nAMD patients at baseline, month 1, and month 2 vs. cataract patients

Angiogenin^a

24,317.3 ± 4154.7

30,190.6 ± 3476.4

0.01584^b

29,507.4 ± 4350.8

0.02178^b

29,965.3 ± 2967.4

0.01380^b

1

BMP-9^a

3.0 ± 0.2

3.2 ± 0.2

0.09101

3.2 ± 0.3

0.02178^b

3.1 ± 0.3

0.09036

1

CCL1/I-309^a

1.0 ± 0.3

1.4 ± 0.24

0.09101

1.7 ± 0.8

0.06525

1.4 ± 0.4

0.23958

1

CCL13/MCP-4^a

6.6 ± 0.9

7.9 ± 1.5

0.06545

8.0 ± 1.9

0.03600^b

7.5 ± 1.6

0.26987

1

CCL2/MCP-1^a

660.3 ± 217.6

1029.6 ± 1214.8

0.25202

1080.2 ± 1392.7

0.06825

869.2 ± 630.3

0.26987

1

CXCL10/IP-10^a

27.3 ± 13.9

48.2 ± 41.2

0.09101

43.8 ± 22.1

0.03600^b

36.5 ± 22.8

0.51063

1

CXCL2/GRO β^a

121.7 ± 24.2

128.5 ± 11.2

0.16895

128.6 ± 24.3

0.54896

130.6 ± 15.7

0.03866^b

1

CXCL8/IL-8^a

61.2 ± 11.0

84.4 ± 45.8

0.03920^b

80.2 ± 30.9

0.06825

76.6 ± 16.3

0.05919

1

Endothelin-1^a

33.4 ± 2.6

37.1 ± 6.6

0.48126

37.8 ± 6.3

0.02547^b

35.8 ± 6.1

1

1

FGF acidic^a

22.7 ± 3.3

26.8 ± 2.3

0.03920^b

28.6 ± 6.7

0.03600^b

28.2 ± 7.6

0.00369^b

1

IL-15^a

4.9 ± 1.8

6.1 ± 1.7

0.16895

6.4 ± 2.5

0.06525

6.0 ± 1.9

0.95610

1

IL-22^a

21.0 ± 3.8

23.4 ± 2.9

0.09101

24.0 ± 3.6

0.03394^b

23.0 ± 2.6

0.11419

1

IL-36 β/IL-1F8^a

1.1 ± 0.7

1.5 ± 0.3

0.03920^b

1.6 ± 0.7

0.02613^b

1.5 ± 0.4

0.01634^b

1

PDGF-BB^a

1.7 ± 0.5

2.4 ± 1.0

0.06545

2.3 ± 0.9

0.03600^b

2.1 ± 0.6

0.47894

1

PlGF^a

4.9 ± 0.5

5.3 ± 0.9

0.06545

4.9 ± 1.1

1

4.7 ± 1.2

1

0.02070^b

TNF-α^a

2.1 ± 0.6

2.4 ± 0.4

0.16895

2.8 ± 1.3

0.02613^b

2.4 ± 0.5

0.70739

1

VEGF-A^a

72.0 ± 21.6

70.6 ± 30.5

1

22.5 ± 1.7

0.00010^b

22.3 ± 1.0

2.88 × 10^−5b

0.00010^b

VEGF-C^a

303.3 ± 47.0

327.0 ± 24.0

0.05820

329.5 ± 39.0

0.03600^b

317.5 ± 35.2

0.45039

1

Angiopoietin-1

105.4 ± 35.3

127.1 ± 67.6

–

126.2 ± 76.1

–

116.4 ± 56.2

–

–

Angiopoietin-2

84.2 ± 16.8

107.1 ± 56.5

–

104.2 ± 57.9

–

101.8 ± 60.7

–

–

CCL20/MIP-3 α

20.9 ± 12.1

20.4 ± 10.7

–

17.8 ± 8.9

–

15.5 ± 7.7

–

–

CCL27/CTACK

4.5 ± 2.1

5.5 ± 1.9

–

5.5 ± 2.2

–

5.2 ± 2.4

–

–

CRP

49,709.8 ± 186,176.6

7566.9 ± 9756.9

–

7132.9 ± 8391.2

–

9574.2 ± 20,248.2

–

–

CXCL16

609.5 ± 132.1

740.2 ± 314.7

–

759.4 ± 324.7

–

739.9 ± 322.5

–

–

Endocan/ESM-1

113.8 ± 35.3

127.6 ± 46.1

–

132.4 ± 51.0

–

126.0 ± 58.0

–

–

FGF basic

17.4 ± 5.3

17.6 ± 6.0

–

16.9 ± 6.5

–

14.5 ± 3.9

–

–

IL-6

8.9 ± 24.1

3.3 ± 5.5

–

6.1 ± 17.3

–

3.9 ± 3.8

–

–

PDGF-AA

37.6 ± 8.8

42.2 ± 10.7

–

41.6 ± 13.5

–

41.1 ± 12.9

–

–