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Table 1 Clinical characteristics in young and senior patient groups

From: Characteristics and outcomes of vitrectomy for proliferative diabetic retinopathy in young versus senior patients

Characteristics

Young patient group

Senior patient group

P-value

Total eyes (patients)

58 (44)

58 (48)

0.359

Age at operation (years)

37.52 ± 5.80

57.60 ± 9.06

< 0.001

Gender (n, %)

 Male

28 (48.3%)

29 (50.0%)

0.853

 Female

30 (51.7%)

29 (50.0%)

0.853

Diabetes mellitus

 History (years)

9.17 ± 6.49

13.98 ± 6.89

< 0.001

 Therapy (n, %)

  Drugs only

10 (17.2%)

11 (19.0%)

0.809

  Drugs and insulin

10 (17.2%)

22 (37.9%)

0.013

  Insulin only

34 (58.6%)

16 (27.6%)

0.001

  Unknown

4 (6.9%)

9 (15.5%)

0.141

 Blood glucose (mmol/L)

6.79 ± 2.26

6.84 ± 2.11

0.905

 Blood pressure (mmHg)

  Systolic blood pressure (mmHg)

149.28 ± 20.37

154.21 ± 22.27

0.197

  Diastolic blood pressure (mmHg)

89.26 ± 9.77

81.22 ± 10.95

< 0.001

Systemic diseases

 Hypertension (n, %)

30 (51.7%)

25 (43.1%)

0.353

 Cardiovascular disorders (n, %)

4 (6.9%)

9 (15.5%)

0.141

 Cerebrovascular disorders (n, %)

6 (10.3%)

9 (15.5%)

0.406

 Kidney disorders (n, %)

27 (46.6%)

12 (20.7%)

0.003

 Renal dialysis (n, %)

6 (13.6%)

2 (4.2%)

0.692

Eyes (n, %)

 Right

31 (53.4%)

27 (46.6%)

0.458

 Left

27 (46.6%)

31 (53.4%)

0.458

Preoperative BCVA (LogMAR)

1.79 ± 0.55

1.73 ± 0.56

0.536

Preoperative IOP (mmHg)

15.93 ± 6.16

14.83 ± 3.27

0.230

Preoperative PRP (n, %)

2 (3.5%)

3 (5.2%)

1.000

Preoperative IVI (n, %)

5 (8.6%)

12 (20.7%)

0.066

Surgical records

 Vitreous tamponade (n, %)

  C3F8

5 (8.6%)

6 (10.3%)

0.751

  Silicone oil

36 (62.1%)

23 (39.7%)

0.016

  BSS

17 (29.3%)

29 (50.0%)

0.023

 Cataract extraction (n, %)

16 (27.6%)

13 (22.4%)

0.520

 Retinotomy (n, %)

24 (41.4%)

10 (17.2%)

0.004

Intraoperative findings (n, %)

 VH only

0 (0.0%)

38 (65.5%)

< 0.001

 FVM with or without VH

22 (37.9%)

13 (22.4%)

0.069

 TRD with or without VH

36 (62.1%)

7 (12.1%)

< 0.001

 Complicated with RVO

24 (41.4%)

20 (34.5%)

0.444

 Complicated with optic atrophy

2 (3.4%)

0 (0.0%)

0.476

Early-postoperative inflammation

6 (10.3%)

1 (1.7%)

0.119

Postoperative complications (n, %)

 Recurrent VH

14 (24.1%)

11 (19.0%)

0.498

 Recurrent RD

2 (3.4%)

0 (0.0%)

0.476

 NVG

16 (27.6%)

1 (1.7%)

< 0.001

 Nuclear sclerosis

31 (53.4%)

2 (3.4%)

< 0.001

Secondary surgery (n, %)

6 (10.3%)

3 (5.2%)

0.298

  1. Values are presented as mean ± standard deviation
  2. BCVA Best corrected visual acuity, IOP Intraocular pressure, PRP Panretinal photocoagulation, IVI Intraocular injection, BSS Balanced salt solution, PPV Pars plana vitrectomy, VH Vitreous hemorrhage, FVM Fibrovascular membrane, TRD Tractional retinal detachment, RVO Retinal vein occlusion, RD Retinal detachment, NVG Neovascular glaucoma