Local use of dexamethasone in the treatment of ocular myasthenia gravis

BMC Ophthalmology

Table 1 General patient information

Patient number	1	2	3	4	5	6	7	8	9	10	11	12	13	14	Average
BCVA
od	0.1	0.1	0.1	0.1	0.1	0.1	0.2	0.1	0.1	0.1	0.1	0.1	0.2	0.1	0.11 ± 0.03
os	0.1	0.1	0.1	0.1	0.1	0.1	0.4	0.1	0.1	0.1	0.1	0.1	0.4	0.1	0.14 ± 0.10
Duration	8	12	3	3	3	6	1	2	4	6	3	3	3	4	4.35 ± 2.84
Neostigmine test	+	+	+	+	+	+	+	+	–	+	–	+	+	+
Thymus CT	–	–	–	–	+	–	–	–	+	+	–	–	–	–
AchR-Ab	–	+	–	+	–	–	+	–	+	+	–	–	–	+
Systemic disease	No	No	No	No	No	No	No	No	No	No	No	No	No	No
History of treatment	No	No	No	Yes	No	No	No	No	No	No	No	No	No	Yes
Ptosis	Bilateral	Left	Right	Bilateral	Right	Left	Bilateral	Right	Bilateral	Right	Left	Right	Right	Bilateral
Diplopia	+	+	+	+	+	+	+	+	+	+	+	+	+	+
Ocular Duction Limitation	+	+	+	–	+	+	+	+	_	+	+	+	–	–
Deviation before treatment (PD)
horizontal^a	−40	−30	−30	−20	−60	−30	− 30	−40.	−20	−40.	−25	−35	−20	+ 20	−28.5 ± 11.1
vertical	2	3	0	0	8	10	20	6	3	5	12	10	0	3	5.85 ± 5.68
Injection site	RMR	LMR	RMR	BMR	RMR	LMR	LMR + LSR	RMR	BMR	RMR	LMR	RMR	RP	RLR
Injection times	6	4	4	4	6	4	2	4	4	5	4	4	4	4	4.23 ± 1.01
Deviation after treatment (PD)
horizontal^a	−5	−3	−3	0	−3	−5	− 30	−5	−3	− 3	−4	0	− 2	+ 3	−4.92 ± 7.38
vertical	0	2	2	3	0	5	10	0	0	0	5	2	0	0	2.07 ± 2.92
Follow up time(months)	25	23	23	21	19	19	–	17	16	13	10	9	8	6	16.0 ± 6.33
Recurrence	NO	NO	NO	NO	NO	NO	–	NO	Yes	NO	NO	NO	NO	Yes

Duration: time from symptom onset to presentation at our institution; AChR Ab acetylcholine receptor antibody; BCVA best-corrected visual acuity; OD right eye; OS left eye; PD prism diopters; RMR right medial rectus muscle: LMR left medial rectus muscle; BMR bilateral medial rectus muscles; LSR left superior rectus muscle; RP right peribulbar area; RLR right lateral rectus muscle
^aAverage horizontal deviation before and after treatment (absolute value)

ISSN: 1471-2415