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Table 1 summaries the characteristics and NOS score of the selected studies

From: The effect of diabetes on corneal endothelium: a meta-analysis

Authors Year Race Country Sample size Gender(M/F) Age Study design Diabetes mellitus type Measure tool NOS
Cases Controls Cases Controls Cases Controls
Keoliean [30] 1992 Caucasians America 14 14 Nm Nm 33 ± 12 33 ± 10 CS Type 1 Widefieldspecular microscope 6
Larsson [31] 1996 Caucasians America 49 20 Nm Nm 36 ± 12 36 ± 12 CS Type 1 Broomall Pa 6
    60 20 Nm Nm 60 ± 10 59 ± 12 CS Type 2 Broomall Pa 6
Siribunkum [32] 2001 Asians Thailand 60 60 20/10 20/10 60.0 ± 9.1 60.4 ± 11.7 CC Type 1 and 2 EM-1020 5
Inoue [33] 2002 Asians Japan 99 97 53/46 52/45 65.5 ± 7.5 67.6 ± 7.3 CS Type 2 NONCON ROBO CA 6
Cho o[34] 2010 Asians Malaysia 100 100 Nm Nm Nm Nm CC Type 2 SP-3000P 7
Jr [35] 2010 Caucasians Hungary 41 40 12/9 13/9 40.97 ± 15.46 40.45 ± 15.16 CS Type 1 EM-1000 7
    59 60 10/20 15/15 64.36 ± 10.47 62.69 ± 13.38 CS Type 2 EM-1000 7
Sudhir [36] 2012 Asians India 1191 120 637/554 58/62 54.8 ± 9.5 51.9 ± 8.7 CS Type 2 SP-8000 6
Paulsen [37] 2013 Caucasians Denmark 107 128 51/56 49/79 72.1 ± 11.0 75.6 ± 8.9 CS Type 2 SP-2000P 6
Urban [38] 2013 Caucasians Poland 123 124 60/63 66/58 15.34 ± 3.06 14.58 ± 2.01 CS Type 1 SP-2000P 6
Arici [39] 2014 Caucasians Turkey 60 109 12/18 18/33 54.8 ± 9.6 53.3 ± 8.2 CS Type 2 SP-3000P 6
Wichi [40] 2015 Asians Thailand 171 156 41/49 34/56 58.49 ± 9.78 58.98 ± 13.12 CS Type 1 and 2 CS 4 4
Galgauskas [41] 2015 Caucasians Lithuania 123 120 31/31 32/33 45.5 ± 13.4 45.4 ± 19.5. CS Type 2 SP-9000 7
Wichai [42] 2016 Asians Thailand 271 82 63/85 16/30 61.04 ± 9.51 57.93 ± 11.30 CS Type 1 and 2 CS 4 5
Islam [43] 2017 Asians Pakistan 149 149 89/60 77/72 54.13 ± 9.97 52.01 ± 12.10 CS Type 1 and 2 SP-3000P 7
Amira [44] 2017 Caucasians Saudi 57 45 27/30 22/23 57.08 ± 8.37 50.80 ± 8.39 CS Type 2 EM-3000 5
Veysel [11] 2018 Caucasians Turkey 153 146 76/77 71/75 54.9 ± 6.6 53.9 ± 7.3 CS Type 2 SP-3000P 7
  1. CS Cross-sectional, CC Case-control, NM Not Mention
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