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Table 1 summaries the characteristics and NOS score of the selected studies

From: The effect of diabetes on corneal endothelium: a meta-analysis

Authors

Year

Race

Country

Sample size

Gender(M/F)

Age

Study design

Diabetes mellitus type

Measure tool

NOS

Cases

Controls

Cases

Controls

Cases

Controls

Keoliean [30]

1992

Caucasians

America

14

14

Nm

Nm

33 ± 12

33 ± 10

CS

Type 1

Widefieldspecular microscope

6

Larsson [31]

1996

Caucasians

America

49

20

Nm

Nm

36 ± 12

36 ± 12

CS

Type 1

Broomall Pa

6

   

60

20

Nm

Nm

60 ± 10

59 ± 12

CS

Type 2

Broomall Pa

6

Siribunkum [32]

2001

Asians

Thailand

60

60

20/10

20/10

60.0 ± 9.1

60.4 ± 11.7

CC

Type 1 and 2

EM-1020

5

Inoue [33]

2002

Asians

Japan

99

97

53/46

52/45

65.5 ± 7.5

67.6 ± 7.3

CS

Type 2

NONCON ROBO CA

6

Cho o[34]

2010

Asians

Malaysia

100

100

Nm

Nm

Nm

Nm

CC

Type 2

SP-3000P

7

Jr [35]

2010

Caucasians

Hungary

41

40

12/9

13/9

40.97 ± 15.46

40.45 ± 15.16

CS

Type 1

EM-1000

7

   

59

60

10/20

15/15

64.36 ± 10.47

62.69 ± 13.38

CS

Type 2

EM-1000

7

Sudhir [36]

2012

Asians

India

1191

120

637/554

58/62

54.8 ± 9.5

51.9 ± 8.7

CS

Type 2

SP-8000

6

Paulsen [37]

2013

Caucasians

Denmark

107

128

51/56

49/79

72.1 ± 11.0

75.6 ± 8.9

CS

Type 2

SP-2000P

6

Urban [38]

2013

Caucasians

Poland

123

124

60/63

66/58

15.34 ± 3.06

14.58 ± 2.01

CS

Type 1

SP-2000P

6

Arici [39]

2014

Caucasians

Turkey

60

109

12/18

18/33

54.8 ± 9.6

53.3 ± 8.2

CS

Type 2

SP-3000P

6

Wichi [40]

2015

Asians

Thailand

171

156

41/49

34/56

58.49 ± 9.78

58.98 ± 13.12

CS

Type 1 and 2

CS 4

4

Galgauskas [41]

2015

Caucasians

Lithuania

123

120

31/31

32/33

45.5 ± 13.4

45.4 ± 19.5.

CS

Type 2

SP-9000

7

Wichai [42]

2016

Asians

Thailand

271

82

63/85

16/30

61.04 ± 9.51

57.93 ± 11.30

CS

Type 1 and 2

CS 4

5

Islam [43]

2017

Asians

Pakistan

149

149

89/60

77/72

54.13 ± 9.97

52.01 ± 12.10

CS

Type 1 and 2

SP-3000P

7

Amira [44]

2017

Caucasians

Saudi

57

45

27/30

22/23

57.08 ± 8.37

50.80 ± 8.39

CS

Type 2

EM-3000

5

Veysel [11]

2018

Caucasians

Turkey

153

146

76/77

71/75

54.9 ± 6.6

53.9 ± 7.3

CS

Type 2

SP-3000P

7

  1. CS Cross-sectional, CC Case-control, NM Not Mention