|
1966
|
Thygeson(America) [3]
|
27
|
7
|
Steroid
|
Effective in suppressing symptoms and the epithelial opacities.
|
|
4
|
IDU(5-iodo-2’-de oxyuridine)
|
Ineffective
|
|
1979
|
Abbott(America) [18]
|
1
| |
Steroids and Artificial tears
|
Remission and recurrence for 16 years
|
|
1979
|
Forstot(America) [25]
|
3
|
1
|
Steroids
|
Relief of symptoms and good visual acuity for over 2 years
|
|
1
|
Dependent on corticosteroids.
|
|
1
|
Soft contact lenses
|
Symptomatic relief
|
|
1980
|
Goldberg(America) [9]
|
4
| |
Soft contact lenses
|
Resolution of the lesions and relief of discomfort.
|
|
1981
|
Tabbara(America) [6]
|
45
|
32
|
Steroid
|
50% of the cases, exacerbation were controlled
|
|
2
|
Soft contact lenses
|
Relieve the symptoms and improve the visual acuity
|
|
10
|
Scrapings
|
No effect on the course of TSPK.
|
|
20
|
IDU and Antibiotics
|
No effect on the course of TSPK.
|
|
1984
|
Nesburn(America) [10]
|
4
| |
Trifluridine therapy
|
Symptoms and later the signs of the disease disappeared
|
|
1999
|
Reinhard(Germany) [23]
|
17
| |
Cyclosporin A 2%
|
71.5% of cases,complete suppression
|
|
2002
|
Reinhard(Germany) [22]
|
28
| |
Cyclosporin A 2%
|
90.5%case improvement
|
|
2001
|
Fite(America) [12]
|
1
| |
PRK
|
Corneal lesions recurrence outside the laser ablation zone
|
|
2002
|
Goldstein(America) [8]
|
1
| |
PRK
|
No recurrences
|
|
2004
|
Nagra(America) [5]
|
40
|
35
|
Steroids
|
Symptomatic relief
|
|
2
|
Artificial tears
|
N/A
|
|
1
|
Soft contact lenses.
|
N/A
|
|
2004
|
Netto(Brazil) [26]
|
1
|
OD
|
PRK
|
No recurrences
|
|
OS
|
LASIK
|
Recurrence after 10 month
|
|
2007
|
Duszak(America) [27]
|
1
| |
Steroid
|
Signs and symptoms disappeared
|
|
2008
|
Hasanreisoglu(Israel) [15]
|
1
| |
Cyclosporin A 0.5%
|
Symptom resolution and corneal clearing
|
|
2011
|
Fintelmann(America) [16]
|
4
| |
Steroids
|
Symptomatic relief and reduce the risk of corneal scarring.
|
|
2015
|
Chao Jiang(China) [28]
|
21
| |
Steroids combined with antiviral drugs
|
17/21cured and 4/21 recurrence
|
|
2015
|
Marquezan(Brazil) [29]
|
14
| |
Tacrolimus 0.03% eye ointment
|
Improved VA, symptoms, and signs
|
