Macular vessel density versus ganglion cell complex thickness for detection of early primary open-angle glaucoma

BMC Ophthalmology

Table 2 GCC thickness in normal, pre-perimetric and early perimetric glaucoma eyes (Mean ± SD)

	GCC thickness (μm)			P value (univariate, multivariate)
	normal	PPG	early PG	a	b
Global	103.4 ± 5.6	92.4 ± 7.9	80.7 ± 10.9	< 0.001, < 0.001	< 0.001, < 0.001
Global SH	103.2 ± 5.6	93.6 ± 8.2	84.2 ± 12.3	< 0.001, < 0.001	< 0.001, 0.001
Global IH	103.6 ± 6.0	91.2 ± 9.4	77.1 ± 12.4	< 0.001, < 0.001	< 0.001, < 0.001
Regional
Para	110.4 ± 8.5	103.9 ± 9.7	89.2 ± 15.9	0.010, < 0.001	< 0.001, < 0.001
Para T	102.5 ± 7.9	96.3 ± 10.5	81.3 ± 13.5	0.015, 0.001	< 0.001, < 0.001
Para S	113.2 ± 9.1	105.6 ± 10.7	93.4 ± 16.0	0.005, 0.001	< 0.001, 0.001
Para N	111.6 ± 9.5	107.1 ± 8.0	92.5 ± 18.7	0.058, < 0.001	< 0.001, < 0.001
Para I	114.3 ± 8.6	106.8 ± 11.5	89.5 ± 20.3	0.007, < 0.001	< 0.001, < 0.001
Peri	103.2 ± 5.7	90.6 ± 8.0	79.5 ± 10.5	< 0.001, < 0.001	< 0.001, < 0.001
Peri T	87.2 ± 4.2	76.4 ± 7.7	68.2 ± 7.9	< 0.001, < 0.001	< 0.001, < 0.001
Peri S	103.1 ± 7.2	90.0 ± 9.8	80.9 ± 14.1	< 0.001, < 0.001	< 0.001, 0.002
Peri N	121.1 ± 7.7	111.2 ± 8.8	98.9 ± 14.4	< 0.001, < 0.001	< 0.001, 0.001
Peri I	101.6 ± 7.3	84.9 ± 11.7	70.1 ± 13.0	< 0.001, < 0.001	< 0.001, < 0.001

Univariate and multivariate analyses using mixed effects model with adjustment for age, gender, and SSI were used to for comparison. The Bonferroni-corrected significance level (0.025) was used for multiple comparisons
GCC Ganglion cell complex, PPG Pre-perimetric glaucoma, PG Perimetric glaucoma, SH Superior hemifield, IH Inferior hemifield, para Parafoveal, peri Perifoveal, T Temporal, S Superior, N Nasal, I Inferior
a. Comparison between the PPG and normal group
b. Comparison between the early PG and normal group

ISSN: 1471-2415